Inheritance of paternal lifestyles and exposures through sperm DNA methylation

KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
DNA methylation is a well-studied epigenetic regulator that is sensitive to … –testis barrier
makes them susceptible to environmental insults. Furthermore, altered sperm DNA methylation

DNA methylation changes induced by prenatal toxic metal exposure: An overview of epidemiological evidence

A Vaiserman, O Lushchak - Environmental Epigenetics, 2021 - academic.oup.com
… that TMs can cross the placental barrier, adversely affect placental functions and accumulate
in fetal tissues. The placenta is known to act as a barrier that protects the growing fetus from …

[HTML][HTML] Mitochondrial DNA methylation and human diseases

A Stoccoro, F Coppedè - International Journal of Molecular Sciences, 2021 - mdpi.com
… investigated in nuclear DNA and include DNA methylation, post-… DNA methylation is
the most widely studied epigenetic … reported that treatment of a blood barrier cell line (hCMEC/D3…

[HTML][HTML] Genome-wide DNA methylation analysis reveals a conserved epigenetic response to seasonal environmental variation in the staghorn coral Acropora …

JA Rodríguez-Casariego… - Frontiers in Marine …, 2020 - frontiersin.org
… Overall, the data generated with this work will serve as a baseline to filter the contribution
of seasonal-driven DNA methylation changes in studies addressing epigenetic responses to …

[HTML][HTML] Zinc and its transporters in epigenetics

S Brito, MG Lee, BH Bin, JS Lee - Molecules and cells, 2020 - Elsevier
Epigenetic events like DNA methylation and histone modification can alter heritable phenotypes.
Zinc is required for the activity of various epigenetic enzymes, such as DNA … skin barrier

[HTML][HTML] The role of DNA methylation in ischemic stroke: a systematic review

M Zeng, J Zhen, X Zheng, H Qiu, X Xu, J Wu… - Frontiers in …, 2020 - frontiersin.org
DNA methylation is one of the most understood epigenetic mechanisms (7). It refers to the
… disrupting the blood-brain barrier or activating cell death signaling pathways (70). The lower …

[HTML][HTML] Genome-wide analysis in the mouse embryo reveals the importance of DNA methylation for transcription integrity

T Dahlet, A Argüeso Lleida, H Al Adhami… - Nature …, 2020 - nature.com
… Our analysis demonstrates that DNA methylation is universally required to maintain …
embryos, confirming that DNA methylation becomes a major epigenetic barrier against transposon …

DNA methylation biomarkers in asthma and rhinitis: are we there yet?

E Legaki, C Arsenis, S Taka… - Clinical and …, 2022 - Wiley Online Library
… Using a state-of-the-art perspective, including the concept of epigenetic aging and machine
… finding was the differential DNA methylation of epithelial barrier genes responsible for …

[HTML][HTML] New insights into the epigenetic regulation of inflammatory bowel disease

J Xu, H Xu, M Yang, Y Liang, Q Peng… - Frontiers in …, 2022 - frontiersin.org
… shown that abnormal epigenetic changes in DNA methylation, … The intestinal barrier and
intestinal flora are also important … regulate the intestinal epithelial barrier and participate in the …

Imprecise DNMT1 activity coupled with neighbor-guided correction enables robust yet flexible epigenetic inheritance

Q Wang, G Yu, X Ming, W Xia, X Xu, Y Zhang… - Nature …, 2020 - nature.com
… For example, the DNA methylome for a clonal population exists as a … that epigenetic mosaicism
is in part due to imprecise DNMT1 activity, which leads to spontaneous DNA methylation ‘…