Burkitt lymphomas evolve to escape dependencies on Epstein-Barr virus

RL Hutcheson, A Chakravorty… - Frontiers in cellular and …, 2021 - frontiersin.org
… , it will be important to attribute mechanisms to the identified mutations so we might further
understand these EBV-associated cancers and their evolution to treat them more effectively. …

Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
treatment of cancers. Adoptive T-cell therapy has been successfully used in the prevention
and treatment … EBV reactivation, termed PTLD that can evolve into Hodgkin lymphoma or non-…

Updated guidelines for chronic active EpsteinBarr virus disease

J Kawada, Y Ito, K Ohshima, M Yamada… - International Journal of …, 2023 - Springer
… the guidelines for the diagnosis and treatment of CAEBV to improve … A standard treatment
approach for CAEBV has not been … lead to clonal evolution involving multiple cell lineages [18]. …

Evolution of functional antibodies following acute Epstein-Barr virus infection

CB Karsten, YC Bartsch, SA Shin, MD Slein… - PLoS …, 2022 - journals.plos.org
While Epstein-Barr virus causes mostly asymptomatic infection, associated malignancies,
and autoimmune and lymphoproliferative diseases occur. To dissect the evolution of humoral …

Treatment options for Epstein-Barr virus-related disorders of the central nervous system

O Andersen, I Ernberg, AK Hedström - Infection and Drug …, 2023 - Taylor & Francis
… Citation5 The virus has co-evolved with humans over millions of years which has resulted
in … treatment options for these disorders and the potential of new therapeutic approaches. …

EpsteinBarr virus in multiple sclerosis: theory and emerging immunotherapies

A Bar-Or, MP Pender, R Khanna, L Steinman… - Trends in molecular …, 2020 - cell.com
… demonstrating a link between B cell-tropic EpsteinBarr virus (EBV) and disease onset.
Efforts to develop antiviral strategies for treating MS are underway. Although gaps remain in our …

Epsteinbarr virus history and pathogenesis

H Yu, ES Robertson - Viruses, 2023 - mdpi.com
… for recognizing and identifying early and effective treatments at different stages in the …
The fact that EBV persists for the lifetime of the host indicates that it has evolved successful …

EpsteinBarr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV

C Venturini, CJ Houldcroft, A Lazareva… - British Journal of …, 2021 - Wiley Online Library
treatment. These findings are compatible with CAEBV being associated with the evolution
and persistence of EBV + haematological clones that are lost on successful treatment. …

Novel therapies boosting T cell immunity in epstein barr virus-associated nasopharyngeal carcinoma

S Renaud, A Lefebvre, S Mordon, O Moralès… - International Journal of …, 2020 - mdpi.com
treatments. Multiple aetiological factors have been described including environmental factors,
genetics, and viral factors (Epstein Barr Virus, EBV), making NPC treatment that … evolution

EpsteinBarr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments

O Shechter, DG Sausen, ES Gallo, H Dahari… - International Journal of …, 2022 - mdpi.com
… Additionally, we discuss and establish which treatments and therapies are most … with
EBV as well as the latest methods of treatment for these conditions. We also mention several …