Targeting estrogen receptors in colorectal cancer
JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
… Abnormal estrogen receptor signaling may increase the risk of development of a variety of
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …
[HTML][HTML] Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes
L Hases, R Indukuri, M Birgersson, T Nguyen-Vu… - Cancer letters, 2020 - Elsevier
… Estrogen hormones protect against colorectal cancer (CRC) and a preventative role of
estrogen receptor beta … To investigate the functional role of intestinal ERβ during colitis-associated …
estrogen receptor beta … To investigate the functional role of intestinal ERβ during colitis-associated …
[HTML][HTML] 17β-estradiol in colorectal cancer: friend or foe?
Z Wu, C Xiao, J Wang, M Zhou, F You, X Li - Cell Communication and …, 2024 - Springer
… As the most potent estrogen, E2 mediates its effects by binding to nuclear estrogen
receptors (ERα, ERβ) and the membrane-associated G protein-coupled estrogen receptor (GPER). …
receptors (ERα, ERβ) and the membrane-associated G protein-coupled estrogen receptor (GPER). …
[HTML][HTML] Estrogen receptor-β signaling induces cisplatin resistance in bladder cancer
T Goto, E Kashiwagi, G Jiang, Y Nagata… - … journal of cancer …, 2020 - ncbi.nlm.nih.gov
… of estrogen receptor-β (ERβ) signals in urothelial cancer … cancer. Immunohistochemistry
in muscle-invasive bladder … In colon cancer cells, E2 inhibited COX-2 by inactivating the …
in muscle-invasive bladder … In colon cancer cells, E2 inhibited COX-2 by inactivating the …
[HTML][HTML] The predictive value of estrogen receptor 1 on adjuvant chemotherapy in locally advanced colorectal cancer: a retrospective analysis with independent …
SB Ye, YK Cheng, R Deng, Y Deng, P Li… - Frontiers in …, 2020 - frontiersin.org
… the tumor expression of estrogen receptor 1 (ESR1) from CRC patients in this context. …
types of estrogen receptor (ER), which is activated by the sex hormone estrogen. Although ESR1 …
types of estrogen receptor (ER), which is activated by the sex hormone estrogen. Although ESR1 …
[HTML][HTML] Estrogen receptor beta (ERβ): a ligand activated tumor suppressor
… that there is an inverse relationship between the expression of ERβ and the presence of
colorectal polyps. The effects of ERβ in colorectal cancer may include reduced metastasis (via …
colorectal polyps. The effects of ERβ in colorectal cancer may include reduced metastasis (via …
[HTML][HTML] The role of estrogen receptor beta in breast cancer
Y Zhou, X Liu - Biomarker research, 2020 - Springer
… cancer necessitate the search for new mechanisms and drugs to improve outcomes. Estrogen
receptor (… The discovery of the second estrogen receptor, ERβ, provides an opportunity to …
receptor (… The discovery of the second estrogen receptor, ERβ, provides an opportunity to …
[HTML][HTML] A role for estrogen receptor alpha36 in cancer progression
MT Pagano, E Ortona, ML Dupuis - Frontiers in Endocrinology, 2020 - frontiersin.org
… of 59 kDa and it is encoded by the gene estrogen receptor 2 (ESR2), located on chromosome
14, … differences in terms of incidence or progression such as melanoma and colon cancer. …
14, … differences in terms of incidence or progression such as melanoma and colon cancer. …
[HTML][HTML] Sexual dimorphism in colon cancer
M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
… examine sexual dimorphism in colorectal cancer (CRC); … Colorectal cancer is the third
most common cancer and the … Disrupted expression of estrogen receptors in the intestinal …
most common cancer and the … Disrupted expression of estrogen receptors in the intestinal …
[HTML][HTML] 17β-Estradiol supplementation changes gut microbiota diversity in intact and colorectal cancer-induced ICR male mice
… The composition of the gut microbiota is influenced by sex hormones and colorectal cancer
(CRC). Previously, we reported that 17β-estradiol (E2) inhibits azoxymethane/dextran sulfate …
(CRC). Previously, we reported that 17β-estradiol (E2) inhibits azoxymethane/dextran sulfate …
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