… Abnormal estrogen receptor signaling may increase the risk of development of a variety of
diseases including colorectal cancer (CRC). Estrogen receptor beta (ERβ) is the predominant …

… Estrogen hormones protect against colorectal cancer (CRC) and a preventative role of
estrogen receptor beta … To investigate the functional role of intestinal ERβ during colitis-associated …

… As the most potent estrogen, E2 mediates its effects by binding to nuclear estrogen
receptors (ERα, ERβ) and the membrane-associated G protein-coupled estrogen receptor (GPER). …

… of estrogen receptor-β (ERβ) signals in urothelial cancer … cancer. Immunohistochemistry
in muscle-invasive bladder … In colon cancer cells, E2 inhibited COX-2 by inactivating the …

… the tumor expression of estrogen receptor 1 (ESR1) from CRC patients in this context. …
types of estrogen receptor (ER), which is activated by the sex hormone estrogen. Although ESR1 …

… that there is an inverse relationship between the expression of ERβ and the presence of
colorectal polyps. The effects of ERβ in colorectal cancer may include reduced metastasis (via …

… cancer necessitate the search for new mechanisms and drugs to improve outcomes. Estrogen
receptor (… The discovery of the second estrogen receptor, ERβ, provides an opportunity to …

… of 59 kDa and it is encoded by the gene estrogen receptor 2 (ESR2), located on chromosome
14, … differences in terms of incidence or progression such as melanoma and colon cancer. …

… examine sexual dimorphism in colorectal cancer (CRC); … Colorectal cancer is the third
most common cancer and the … Disrupted expression of estrogen receptors in the intestinal …

… The composition of the gut microbiota is influenced by sex hormones and colorectal cancer
(CRC). Previously, we reported that 17β-estradiol (E2) inhibits azoxymethane/dextran sulfate …