… fibroproliferation and deposition of excessive extracellular matrix explaining some of the
observed clinical features of Myhre syndrome… gross and pathologic findings in Myhre syndrome. …

… a striking fibroproliferative response in the ear canals, airways, and serosal cavities (peritoneum,
pleura, pericardium). Confirmation of the clinical diagnosis is usually prompted by the …

… Myhre syndrome is an increasingly diagnosed ultrarare condition caused by recurrent
germline autosomal dominant de novo variants in SMAD4. Detailed multispecialty evaluations …

… PubMed was queried with the search term ‘Myhre syndrome’. Articles published after
December, 2011 (when the molecular cause of MS was published) until June 16, 2023 were …

… Moreover, patients with MS can have a markedly abnormal fibroproliferative response to
surgical intervention. Therefore, surgical intervention should be approached with extreme …

… Autism Spectrum Disorder), and a fibroproliferative response. … the central nervous system in
Myhre syndrome, a systematic … General Hospital (MGH) Myhre Syndrome Clinic. We wanted …

… markedly abnormal fibroproliferative response to surgical intervention, tissue damage, or
instrumentation has been reported as a complication in patients with Myhre syndrome. Mild …

… Autism Spectrum Disorder), and a fibroproliferative response. … the central nervous system in
Myhre syndrome, a systematic … General Hospital (MGH) Myhre Syndrome Clinic. We wanted …

… beneficial adaptive response in cardiac disease, which … response, such as asthma, pulmonary
fibrosis, rheumatoid arthritis, collagen vascular diseases, sepsis, trauma, fibroproliferative …

… Myhre syndrome (OMIM #139210) is characterized by muscle hypertrophy, midface hypoplasia,
blepharophimosis, prognathism, intellectual disability, short stature, brachydactyly, and …