Ganciclovir therapeutic drug monitoring in transplant recipients
… exposure targets in ganciclovir therapy remains and to observe underexposure linked with
failure of therapy requires analysis of a wider patient population. Still, ganciclovir remains a …
failure of therapy requires analysis of a wider patient population. Still, ganciclovir remains a …
Optimization of Ganciclovir use in allogeneic hematopoietic cell transplant recipients–the role of therapeutic drug monitoring
… The mainstay of treatment and prevention of this infection is ganciclovir and its ester prodrug
… of routine ganciclovir therapeutic drug monitoring (TDM) as a means to optimize treatment. …
… of routine ganciclovir therapeutic drug monitoring (TDM) as a means to optimize treatment. …
Emergence of letermovir resistance in solid organ transplant recipients with ganciclovir resistant cytomegalovirus infection: A case series and review of the literature
E Hofmann, D Sidler, S Dahdal, P Bittel… - Transplant Infectious …, 2021 - Wiley Online Library
… Letermovir resistance in our two renal transplant recipients emerged after a few months
of secondary prophylaxis: In case one, letermovir resistance was detected after 106 days of …
of secondary prophylaxis: In case one, letermovir resistance was detected after 106 days of …
[HTML][HTML] Oral antiviral drugs for treatment of cytomegalovirus in transplant recipients
RR Razonable - Clinical Microbiology and Infection, 2023 - Elsevier
… Lack of satisfactory virologic and clinical response after 2–3 weeks of ganciclovir treatment
suggests refractory CMV [5]. Many, but not all, refractory CMV infections are because of the …
suggests refractory CMV [5]. Many, but not all, refractory CMV infections are because of the …
Detection of ganciclovir-resistant cytomegalovirus in a prospective cohort of kidney transplant recipients receiving subtherapeutic valganciclovir prophylaxis
DD Wong, WJ van Zuylen, T Novos… - Microbiology …, 2022 - Am Soc Microbiol
… of ganciclovir-resistant CMV variants, despite this being biologically plausible. The molecular
determinants of ganciclovir … and ganciclovir exposure in kidney transplant recipients and to …
determinants of ganciclovir … and ganciclovir exposure in kidney transplant recipients and to …
Combination treatment with letermovir and ganciclovir for maintenance therapy of multidrug-resistant CMV infection in a liver transplant recipient
I Kronig, L Elkrief, T Berney, C Van Delden… - …, 2020 - journals.lww.com
… a liver transplant recipient, cytomegalovirus (CMV) donor-positive (D+), recipient-negative (…
CMV infection treated with a combination therapy of letermovir and (val)ganciclovir (Figure 1). …
CMV infection treated with a combination therapy of letermovir and (val)ganciclovir (Figure 1). …
… review of the clinical pharmacokinetics, pharmacodynamics and toxicodynamics of ganciclovir/valganciclovir in allogeneic haematopoietic stem cell transplant patients
PR Selby, S Shakib, SL Peake, MS Warner… - Clinical …, 2021 - Springer
… A study of oral GCV in lung transplant recipients showed a significant correlation of C max
and C min with AUC, with a standard dose of 1 g three times daily [68]. However, considering …
and C min with AUC, with a standard dose of 1 g three times daily [68]. However, considering …
Population pharmacokinetics of ganciclovir in allogeneic hematopoietic stem cell transplant patients
PR Selby, AJ Heffernan, D Yeung… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
… at the initiation of ganciclovir therapy was 79 mL/min (range 31 to 153) excluding 2 (10%) …
patients received prior to sampling was 2. Dose, frequency, and the ganciclovir treatment day …
patients received prior to sampling was 2. Dose, frequency, and the ganciclovir treatment day …
Pharmacokinetics, pharmacodynamics, and therapeutic drug monitoring of valganciclovir and ganciclovir in transplantation
B Franck, J Autmizguine, P Marquet… - Clinical …, 2022 - Wiley Online Library
… in solid organ and stem cell transplant recipients. Only a few … of ganciclovir and valganciclovir
in transplant recipients have … parameter to use for therapeutic drug monitoring (TDM). We …
in transplant recipients have … parameter to use for therapeutic drug monitoring (TDM). We …
Ganciclovir pharmacokinetics and individualized dosing based on covariate in lung transplant recipients
E Dvořáčková, M Šíma, J Petrus, E Klapková… - Pharmaceutics, 2022 - mdpi.com
… reviewed the pharmacokinetics of ganciclovir in patients after lung transplantation, on whom
… transplant recipients. This represents one of the largest data sets describing ganciclovir …
… transplant recipients. This represents one of the largest data sets describing ganciclovir …
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