Functional roles of connexins and gap junctions in osteo-chondral cellular components
A Zappalà, IR Romano, F D'Angeli… - International Journal of …, 2023 - mdpi.com
… Synovial tissue produces synovium, a fluid that lubricates the joints and supplies nutrients
to articular chondrocytes. Alterations of this communication network are assumed to be …
to articular chondrocytes. Alterations of this communication network are assumed to be …
PDGF-AA promotes gap junction intercellular communication in chondrocytes via the PI3K/Akt pathway
S Xu, Y Liu, D Zhang, H Huang, J Li, J Wei… - Connective Tissue …, 2022 - Taylor & Francis
… on gap junctions in chondrocytes and the underlying mechanism. To examine the effects of
PDGF-AA on cell communication, we assessed functional gap junction … the signaling network …
PDGF-AA on cell communication, we assessed functional gap junction … the signaling network …
CTGF facilitates cell‐cell communication in chondrocytes via PI3K/Akt signalling pathway
Z Wu, C Zhou, Q Yuan, D Zhang, J Xie… - Cell proliferation, 2021 - Wiley Online Library
… Our results confirmed that CTGF promoted this gap junction formation in chondrocytes (…
network communication between chondrocytes (Figure 1L). Accordingly, siRNA of CTGF in …
network communication between chondrocytes (Figure 1L). Accordingly, siRNA of CTGF in …
[HTML][HTML] TGF-β2 increases cell-cell communication in chondrocytes via p-Smad3 signalling
M Duan, Y Liu, D Guo, S Kan, Z Niu, X Pu, M Bai… - … et Biophysica Acta (BBA …, 2022 - Elsevier
… Gap junctions are composed of different gap junction … profile of the gap junction protein
family in chondrocytes. We … into the trans-Golgi network through coat protein complex II (COPII), …
family in chondrocytes. We … into the trans-Golgi network through coat protein complex II (COPII), …
Nanoscale ligand density modulates gap junction intercellular communication of cell condensates during chondrogenesis
… This observation, together with the results of condensate stability and GJIC, indicates that
the establishment of a functional GJ network during hASCs chondrogenic condensation is an …
the establishment of a functional GJ network during hASCs chondrogenic condensation is an …
Biomaterial stiffness guides cross-talk between chondrocytes: implications for a novel cellular response in cartilage tissue engineering
L Cai, W Liu, Y Cui, Y Liu, W Du, L Zheng… - ACS Biomaterials …, 2020 - ACS Publications
… junctional proteins including connexin 43 (Cx43) and pannexin 1 (Panx1), which are
responsible for gap junction … LY transportation networks connecting different living chondrocytes. …
responsible for gap junction … LY transportation networks connecting different living chondrocytes. …
Integrins, cadherins and channels in cartilage mechanotransduction: perspectives for future regeneration strategies
MP Dieterle, A Husari, B Rolauffs… - Expert Reviews in …, 2021 - cambridge.org
… Regarding the latter, mechanotransduction of chondrocytes and … channels and gap junctions
additionally govern chondrocyte … It has been concluded that a 3D cellular network mediated …
additionally govern chondrocyte … It has been concluded that a 3D cellular network mediated …
IL-10 enhances cell-to-cell communication in chondrocytes via STAT3 signaling pathway
D Guo, S Kan, L Zhang, Z Niu, M Duan, Y Liu, X Pu… - Cellular …, 2023 - Elsevier
… To investigate the functional gap junction formation in chondrocytes, we did a scrape … by
fluorescent LY and gap junction networks induced by IL-10. We found that IL-10 could enhance …
fluorescent LY and gap junction networks induced by IL-10. We found that IL-10 could enhance …
Fibroblast growth factor 8 facilitates cell-cell communication in chondrocytes via p38-MAPK signaling
X Cao, L Cai, D Guo, D Zhang, X Zhou, J Xie - Tissue and Cell, 2023 - Elsevier
… by the up-regulation of connexin43 (Cx43), the major fundamental component unit of gap
junction channels in chondrocytes. FGF8 activated p38-MAPK signaling to increase the …
junction channels in chondrocytes. FGF8 activated p38-MAPK signaling to increase the …
The role of gap junctions in endothelial–stromal cell interactions
MI Ezdakova, DK Matveeva, SV Buravkov… - Human Physiology, 2021 - Springer
… the physiological homeostasis of the vascular network but also plays an important role in the
… During cultivation, such chondrocytes retained the ability to form voltage-dependent GJs [71]…
… During cultivation, such chondrocytes retained the ability to form voltage-dependent GJs [71]…
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