[PDF][PDF] Ultrastructure of gap junction and Cx43 expression in gastric cancer tissues of the patients

CH Li, ML Hao, Y Sun, ZJ Wang, JL Li - Archives of Medical Science, 2020 - termedia.pl
gap junction and its connexins such as Cx43 involved in gastric cancer remain necessary.
This study investigated the changes in gap junction ultrastructure and Cx43 in normal gastric …

Connexin 43 across the vasculature: Gap junctions and beyond

MW Sedovy, X Leng, MR Leaf, F Iqbal… - Journal of vascular …, 2023 - karger.com
… of Cx43 gap junctions [28]. Here, we review the role of Cx43 in the vasculature, including its
gap junction… showed a reduction in Cx43 expression and impaired gap junction activity [112, …

Gap junction-dependent and-independent functions of Connexin43 in biology

Y Zhu - Biology, 2022 - mdpi.com
Cx43 connexons from two cells form a complete gap junction. A few Cx43 gap junctions
The ectopic expression of Cx43-20k protects against Cx43 gap junction loss during acute …

Altered expression of glial gap junction proteins Cx43, Cx30, and Cx47 in the 5XFAD model of Alzheimer's disease

S Angeli, I Kousiappa, M Stavrou… - Frontiers in …, 2020 - frontiersin.org
… Moreover, Cx47 GJ plaques showed reduced colocalization with Cx43gap junction
connectivity and possibly a shift in Cx43 expression toward astrocyte-astrocyte gap junctions and/or …

[HTML][HTML] BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution

C Chai, K Sui, J Tang, H Yu, C Yang, H Zhang, SC Li… - Theranostics, 2023 - ncbi.nlm.nih.gov
… Consistent with other reports 24 , we previously showed that the decreased Cx43 expression
is associated with the disturbed GJIC function of BMSCs in LME 25 , 26 . Conversely, …

Expression of Connexin43 stimulates endothelial angiogenesis independently of gap junctional communication in vitro

C Koepple, Z Zhou, L Huber, M Schulte… - International Journal of …, 2021 - mdpi.com
expression of Cx43 enhances the angiogenic potential of endothelial cells in a gap junction
… To test this hypothesis, we examined the effects of Cx43 up- and downregulation in human …

Remodeling of cardiac gap junctional cell–cell coupling

S Dhein, A Salameh - Cells, 2021 - mdpi.com
… These gap junction channels can be homotypic Cx43 and Cx45, and heterotypic … expression,
resulting in altered gap junction density and functional coupling, as well as changes in …

Human Cx50 Isoleucine177 prevents heterotypic docking and formation of functional gap junction channels with Cx43

RS Wong, H Chen, YX Li, JL Esseltine… - … of Physiology-Cell …, 2024 - journals.physiology.org
expressed in lens fibre cells and Cx43 and Cx50 in the epithelial cells. Impairment of GJ 28
… dependent on gap junction 45 (GJ) network composed of Cx46, Cx50, and Cx43. We found …

EHD1 modulates Cx43 gap junction remodeling associated with cardiac diseases

T Martins-Marques, S Catarino, A Gonçalves… - Circulation …, 2020 - Am Heart Assoc
… mainly ensured by gap junctions (GJ) localized at the intercalated discs (IDs). GJ are formed
by 4-pass transmembrane Cx (connexins), of which Cx43 is the most expressed in the heart…

The role of the Cx43/Cx45 gap junction voltage gating on wave propagation and arrhythmogenic activity in cardiac tissue

K Maciunas, M Snipas, T Kraujalis, L Kraujalienė… - Scientific reports, 2023 - nature.com
… Mainly, our simulation data show that the arrangement of heterotypic Cx43/Cx45, which is
suggested by the expression patterns of cardiac Cxs, would be consistent with the principal …