[HTML][HTML] Comparison of first-generation EGFR-TKIs (gefitinib, erlotinib, and icotinib) as adjuvant therapy in resected NSCLC patients with sensitive EGFR mutations

Q He, J Liu, X Cai, M He, C Li, H Liang… - … Cancer Research, 2021 - ncbi.nlm.nih.gov
… This is a retrospective study of a prospectively maintained cohort. The aims of this study were
to compare the efficacy among three first-generation EGFR-TKIs as adjuvant treatment and …

[HTML][HTML] The different central nervous system efficacy among gefitinib, erlotinib and afatinib in patients with epidermal growth factor receptor mutation-positive non …

HA Jung, SY Woo, SH Lee, JS Ahn… - … Cancer Research, 2020 - ncbi.nlm.nih.gov
… 17.3 months for gefitinib, 12.4 months for erlotinib, and 23.3 … –0.83) compared with gefitinib
or erlotinib. In the competing … failure compared with gefitinib or erlotinib after adjusting for both …

Survival benefits from afatinib compared with gefitinib and erlotinib among patients with common EGFR mutation in first‐line setting

WC Kwok, JCM Ho, TCC Tam, MSM Ip… - Thoracic …, 2022 - Wiley Online Library
… A retrospective cohort study of Chinese patients with metastatic NSCLC harboring EGFR
mutations who received first-line gefitinib, erlotinib or afatinib treatment, followed by osimertinib …

Comparing the effectiveness of different EGFR‐TKIs in patients with EGFR mutant non–small‐cell lung cancer: a retrospective cohort study in Taiwan

YY Hsieh, WT Fang, YW Lo, YH Chen… - International journal of …, 2020 - Wiley Online Library
… This retrospective cohort study was conducted using data from real-world settings. Patients
with stage IIIB and IV NSCLC and first received gefitinib, erlotinib, or afatinib between 2011 …

Nationwide real-world cohort study of first-line tyrosine kinase inhibitor treatment in epidermal growth factor receptor-mutated non–small-cell lung cancer

RGP Gijtenbeek, RAM Damhuis, HJM Groen… - Clinical lung cancer, 2020 - Elsevier
erlotinib, we observed a poorer adjusted survival for gefitinib … , this study is the largest
European real-world cohort of … erlotinib, we observed a poorer adjusted survival for gefitinib

Proton pump inhibitors reduce the survival of advanced lung cancer patients with therapy of gefitinib or erlotinib

CH Lee, MC Shen, MJ Tsai, JS Chang, YB Huang… - Scientific Reports, 2022 - nature.com
… -based cohort study demonstrated that concurrent PPI with gefitinib or erlotinib was
associated with significantly poorer OS and TTNT than the H2RA and non-user. Other studies

First-or second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large, real-world cohort of patients with non-small cell lung cancer

ACC Huang, CH Huang, JS Ju… - Therapeutic …, 2021 - journals.sagepub.com
… The slightly higher T790M yield of both the gefitinib/erlotinib and afatinib groups in the
present study might be related to the addition of a liquid biopsy when a tissue biopsy was …

… kinase inhibitors first-line in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer: A retrospective observational cohort study

WW Ng, CC Lin, CY Cheng, JS Jiang, SJ Kao, DY Yeh - Plos one, 2021 - journals.plos.org
gefitinib and afatinib groups (p = 0.009). Patients on afatinib also had longer median OS than
erlotinib and gefitinib … a better choice compared to gefitinib or erlotinib for EGFRm+ patients…

Clinical outcomes of gefitinib and erlotinib in patients with NSCLC harboring uncommon EGFR mutations: A pooled analysis of 438 patients

C Wang, K Zhao, S Hu, W Dong, Y Gong, M Li, C Xie - Lung Cancer, 2022 - Elsevier
… The purpose of this study was to investigate the outcomes of gefitinib and erlotinib in patients
with non-small cell lung cancer (NSCLC) with uncommon epidermal growth factor receptor (…

Outcomes in patients with lung cancer treated with crizotinib and erlotinib in routine clinical practice: A post‐authorization safety cohort study conducted in Europe and …

V Ehrenstein, K Huang, J Kahlert… - … and Drug Safety, 2021 - Wiley Online Library
erlotinib or gefitinib, we excluded patients with a previous dispensing of erlotinib or gefitinib;
and … patient entered one of the 4 cohorts: crizotinib cohort; ceritinib cohort; erlotinib cohort, or …