DNA methylation and histone modifications are essential for regulation of stem cell formation and differentiation in zebrafish development

AD Marchione, Z Thompson… - … in functional genomics, 2021 - academic.oup.com
… , including methylation and acetylation of specific lysine (K) residues, are established on
histones [3]. Genomes undergo global methylation changes to stabilize DNA methylation levels …

[HTML][HTML] Developmental accumulation of gene body and transposon non-CpG methylation in the zebrafish brain

SE Ross, D Hesselson, O Bogdanovic - Frontiers in Cell and …, 2021 - frontiersin.org
DNA methylation predominantly occurs at CG dinucleotides in vertebrate genomes; however,
non-CG methylation (mCH) is also detectable in vertebrate tissues, most notably in the …

Ionising radiation induces promoter DNA hypomethylation and perturbs transcriptional activity of genes involved in morphogenesis during gastrulation in zebrafish

S Murat El Houdigui, C Adam-Guillermin… - International Journal of …, 2020 - mdpi.com
… To assess whether IR can modify epigenetic marks and thereby modulate transcriptional
activity, we analysed DNA methylation at the whole genome scale using WGBS on shield stage …

DNA methylation of pck1 might contribute to the programming effects of early high-carbohydrate diets feeding to the glucose metabolism across two generations in …

K Lu, XF Liang, T Liu, W Cai, W Zhuang… - Fish Physiology and …, 2022 - Springer
… Further, we evaluated the DNA methylation statute of phosphoenolpyruvate carboxykinase
1 (… detection of changes in genomic DNA methylation during early zebrafish development. …

DNA methylation profiles suggest intergenerational transfer of maternal effects

CJ Venney, OP Love, EJ Drown… - Molecular Biology and …, 2020 - academic.oup.com
… occur at specific life stages after methylation reset, but before the offspring gains autonomy
over their genome. Regardless, our results support DNA methylation as a potential novel …

Transgenerational inheritance of impaired larval T cell development in zebrafish

N Iwanami, DF Lawir, K Sikora, CO´ Meara… - Nature …, 2020 - nature.com
… of aberrant DNA methylation patterns associated with impaired larval T cell development. …
Moreover, DMRs exhibiting dynamic changes during early zebrafish development, such as …

[HTML][HTML] Chromatin dynamics at the maternal to zygotic transition: recent advances from the zebrafish model

B Akdogan-Ozdilek, KL Duval, MG Goll - F1000Research, 2020 - ncbi.nlm.nih.gov
… dynamics during early zebrafish development, highlighting … of DNA methylation on the
maternal genome during early … virtually all regions lacking DNA methylation, and perturbation of …

[HTML][HTML] Microarray transcriptome datasets of maternal-zygotic DNA methyltransferase 3aa−/− zebrafish during early developmental stages

M Shirai, N Shimoda, H Takahashi, K Takayama… - Data in Brief, 2023 - Elsevier
… in DNA methylation in the distinct or overlapping genomic … regions for DNA methylation in
the zebrafish genome and their … -out of dnmt3aa in early zebrafish development. Microarray …

Nuclear organization during hepatogenesis in zebrafish requires Uhrf1

BP Madakashira, C Zhang, F Macchi, E Magnani… - Genes, 2021 - mdpi.com
… by the pattern of DNA methylation. Using the morphological assessment of the nuclear lamina
and nucleolus coupled with chromatin accessibility, DNA methylation, and transcriptomics, …

Using zebrafish embryo bioassays to identify chemicals modulating the regulation of the epigenome: a case study with simvastatin

T Torres, S Barros, T Neuparth, R Ruivo… - … Science and Pollution …, 2023 - Springer
… Therefore, as a complementary approach, we determined the global DNA methylation levels
in F1 generation embryos, which were depressed at the two highest tested concentrations (…