[HTML][HTML] Plasma membrane integrity in health and disease: significance and therapeutic potential

C Dias, J Nylandsted - Cell discovery, 2021 - nature.com
heart failure are high and there is no cure for this common terminal illness 89 . Although
heart failure … , including myocardial infarction, promote heart failure 89 . Acute myocardial …

Patient profiling in heart failure for tailoring medical therapy. A consensus document of the Heart Failure Association of the European Society of Cardiology

GMC Rosano, B Moura, M Metra… - … of heart failure, 2021 - Wiley Online Library
… Treatment of patients with heart failure (HF) and a reduced ejection fraction (HFrEF) is …
reflected in the European Society of Cardiology/Heart Failure Association (ESC/HFA) guidelines, …

Oxidative stress and inflammation in the evolution of heart failure: from pathophysiology to therapeutic strategies

A Aimo, V Castiglione, C Borrelli… - European journal of …, 2020 - journals.sagepub.com
… pathophysiology, with the ultimate goal of improving the care of heart failure patients. …
elements of heart failure syndrome and potential contributors to heart failure progression. While …

[HTML][HTML] Signaling cascades in the failing heart and emerging therapeutic strategies

X He, T Du, T Long, X Liao, Y Dong… - … and targeted therapy, 2022 - nature.com
… Chronic heart failure is the end stage of cardiac diseases. With a … heart failure is one of the
heaviest health-related burdens. In addition to the standard neurohormonal blockade therapy, …

Mitochondrial dysfunction and mitochondrial therapies in heart failure

C Wu, Z Zhang, W Zhang, X Liu - Pharmacological Research, 2022 - Elsevier
heart. This article reviews the recent findings on the role of mitochondrial dysfunction in heart
failure, … effects to provide insights into mitochondrial therapies for heart failure treatment. …

[HTML][HTML] Pathophysiology of heart failure

RHG Schwinger - Cardiovascular diagnosis and therapy, 2021 - ncbi.nlm.nih.gov
… Genetic profiles may influence risk and prognosis as well as therapeutic options of heart
failure eg, defibrillator implantation in high risk mutations for hypertrophy. Heart failure patients …

Iron and heart failure: diagnosis, therapies, and future directions

K Ghafourian, JS Shapiro, L Goodman… - Basic to Translational …, 2020 - jacc.org
… Therefore, intravenous iron may be administered to heart failureheart failure and iron
deficiency, sufficient consideration should be given to the route of administration and the potential

[HTML][HTML] Cardiac regeneration: new insights into the frontier of ischemic heart failure therapy

AS Riching, K Song - Frontiers in Bioengineering and Biotechnology, 2021 - frontiersin.org
… A key development in the treatment of heart failure post-MI was the pioneering of surgical
intervention to revascularize the infarcted myocardium via removal of coronary artery …

Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence

Y Tan, Z Zhang, C Zheng, KA Wintergerst… - Nature Reviews …, 2020 - nature.com
… underlying the development of diabetic cardiomyopathy and heart failure in type 1 and
type 2 … therapeutic strategies for the treatment and prevention of diabetic cardiomyopathy. …

Tissue sodium storage in patients with heart failure: a new therapeutic target?

S Lemoine, FR Salerno, A Akbari… - Circulation …, 2021 - Am Heart Assoc
… challenge when treating patients with heart failure, excessive nonosmotically active tissue
sodium storage seems to be a characteristic feature of severe heart failure. These levels of …