… Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating
biomarkers reflecting pathophysiological pathways involved in HF development and …

… have therapeutic value. However, the effects of mitochondrial ROS seem to be context-dependent,
limiting the therapeutic potential of antioxidant therapy… remodeling in heart failure. For …

… in heart failure and arrhythmia. The hawthorn extract demonstrates efficacy in the treatment
of heart failure, … in wine, has shown efficacy against heart failure in isolated tissues or organs, …

… in heart failure (HF) and hypertension [22,1,23]. The RAS was once thought to be a
comparatively lesser complex signaling pathway; nevertheless, with due course of time, it has been …

… The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point, epidemiological, …

… central to the pathophysiology of heart failure. Increased extracellular fluid … heart failure
referred to as congestion. Loop diuretics are one of the cornerstones of treatments for heart failure…

… Limited data in humans suggest that ketone supplementation has therapeutic potential in
HF. In a randomized, crossover study in patients with compensated HFrEF, a 3-hour infusion of …

… of heart failure, sparking renewed interest in this area. … the heart failure setting. The immune
system also has an important role in acute decompensated heart failure and in heart failure …

… cardiomyopathy with heart failure. There is no established treatment other than standard
heart failure therapy or heart … the efficacy of established heart failure therapies eplerenone or …

… for this type of heart failure, which now represents more than half of all heart failure cases
worldwide. Similar to the readily characterized heart failure with reduced ejection fraction (…