Aims Cardiac microRNA-132-3p (miR-132) levels are increased in patients with heart
failure (HF) and mechanistically drive cardiac remodelling processes. CDR132L, a specific …

… To further assess the therapeutic potential of antimiR-132, we designed a large animal …
of remodeling in both treatment arms reinforces the therapeutic potential of our compound. …

… A wide range of histone deacetylase (HDAC) inhibitors have been studied for their therapeutic
potential because the excessive activity and expression of HDACs have been implicated …

… CB 1 R antagonists and their potential therapeutic uses in this review, which is dedicated
to Dr. Gerard Le Fur who first recognized the therapeutic potential of CB 1 R antagonism. …

… Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality, and …

… This review mainly focuses on the therapeutic potential of pyrrole, pyrrolidine, and its fused
… Ramipril is used to treat hypertension, congestive heart failure, and to control the death rate […

… heart failure (compared with heart failure with reduced ejection fraction). C, NPs are active
in adipose tissue, where the relative ratio of the NP receptor A (NPRA) to NP receptor C (RC) …

… therapeutic potential of targeting m 6 A regulators in disease. … m 6 A may hold therapeutic
potential in this setting (Barbieri et al, … the therapeutic potential of targeting m 6 A regulators. …

… heart failure is approximately 26 million patients, and the current estimates of the incidence
and prevalence of heart failure … declines in the incidence of heart failure can be attributed to a …

… drugs for chronic heart failure (HF), giving rise to a new debate regarding appropriate
background therapy against which to study novel therapeutics. The Heart Failure Collaboratory, a …