Gene therapy for the heart lessons learned and future perspectives

A Cannatà, H Ali, G Sinagra, M Giacca - Circulation research, 2020 - Am Heart Assoc
… a therapeutic gene expression cassette substitutes the viral E1 and/or E3 regions, have
advanced to clinical trials for applications in both therapeutic angiogenesis and heart failure. …

[HTML][HTML] Therapeutic potential of resveratrol against emerging respiratory viral infections

S Filardo, M Di Pietro, P Mastromarino… - … & therapeutics, 2020 - Elsevier
… Resveratrol has been widely studied for its therapeutic potential due to its antioxidant, anti-inflammatory
and anti-microbial properties. In particular, resveratrol has shown promising …

[PDF][PDF] Heart Failure and Biomarkers. Unravelling new pathophysiological pathways, outcome predictors, and therapeutic targets.

A Salzano - 2021 - core.ac.uk
… This section is a review written with regard to the role of blood biomarkers and imaging in
heart failure for the Heart failure clinic journal. As conclusion, the multi-biomarkers strategy, in …

Targeting gut microbiota as a novel strategy for prevention and treatment of hypertension, atrial fibrillation and heart failure: current knowledge and future perspectives

OM Drapkina, AA Yafarova, AN Kaburova, AR Kiselev - Biomedicines, 2022 - mdpi.com
… Recent evidence has shed light on the therapeutic potential of the modulation of both GMB
and microbial metabolites in selected CVDs. The main therapeutic strategies designed to …

Regulatory RNAs in heart failure

CPC Gomes, B Schroen, GM Kuster, EL Robinson… - Circulation, 2020 - Am Heart Assoc
… survival have led to the increasing prevalence of heart failure in the US population 3 and in
… in aspects of heart failure and their potential as novel clinical and therapeutic biomarkers. We …

Cardiac energy metabolism in heart failure

GD Lopaschuk, QG Karwi, R Tian, AR Wende… - Circulation …, 2021 - Am Heart Assoc
… of the energy metabolic changes that occur in heart failure. This includes distinguishing the
… , as well as heart failure associated with diabetes (ie, diabetic cardiomyopathy). Although we …

Congestion in heart failure: a contemporary look at physiology, diagnosis and treatment

EM Boorsma, JM Ter Maaten, K Damman… - Nature reviews …, 2020 - nature.com
… with acute decompensated heart failure and is an important target for therapy. However, …
the outcomes of patients with acute decompensated heart failure. Although the majority of these …

A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

S Fuloria, J Mehta, A Chandel, M Sekar… - Frontiers in …, 2022 - frontiersin.org
… longa, is well known for its therapeutic potential in numerous disorders. However, there is
a lack of literature on the therapeutic potential of C. longa in contrast to curcumin. Hence, the …

Acute heart failure

M Arrigo, M Jessup, W Mullens, N Reza… - Nature Reviews …, 2020 - nature.com
… (AHF) is a syndrome defined as the new onset (de novo heart failure (HF)) or worsening (acutely
decompensated heart failure (ADHF)) of symptoms and signs of HF, mostly related to …

Medical therapies for heart failure with preserved ejection fraction

SE Kjeldsen, TG von Lueder, OA Smiseth… - …, 2020 - Am Heart Assoc
… -risk hypertension and heart failure with reduced ejection fraction, … in hypertension and heart
failure with reduced ejection … cardiovascular disease from hypertension to heart failure (HF). …