[HTML][HTML] Therapeutic potential of metformin in COVID-19: reasoning for its protective role

SM Samuel, E Varghese, D Büsselberg - Trends in microbiology, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections present with
increased disease severity and poor clinical outcomes in diabetic patients compared with their …

The effect of spironolactone on cardiovascular function and markers of fibrosis in people at increased risk of developing heart failure: the heart 'OMics' in AGEing …

JGF Cleland, JP Ferreira, B Mariottoni… - European heart …, 2021 - academic.oup.com
… to symptomatic heart failure should be investigated. … biomarkers for predicting incident heart
failure in older people … people at increased risk of developing heart failure. The protocol and …

Gene therapy for the heart lessons learned and future perspectives

A Cannatà, H Ali, G Sinagra, M Giacca - Circulation research, 2020 - Am Heart Assoc
… a therapeutic gene expression cassette substitutes the viral E1 and/or E3 regions, have
advanced to clinical trials for applications in both therapeutic angiogenesis and heart failure. …

Compression therapy for leg oedema in patients with heart failure

T Urbanek, M Juśko, WB Kuczmik - ESC heart failure, 2020 - Wiley Online Library
… , obesity, renal failure, and chronic heart failure (CHF). In most of these clinical conditions,
the presence of leg swelling is usually secondary to the primary disease [eg heart failure (HF)], …

[HTML][HTML] Therapeutic potential of resveratrol against emerging respiratory viral infections

S Filardo, M Di Pietro, P Mastromarino… - … & therapeutics, 2020 - Elsevier
… Resveratrol has been widely studied for its therapeutic potential due to its antioxidant, anti-inflammatory
and anti-microbial properties. In particular, resveratrol has shown promising …

Regulatory RNAs in heart failure

CPC Gomes, B Schroen, GM Kuster, EL Robinson… - Circulation, 2020 - Am Heart Assoc
… survival have led to the increasing prevalence of heart failure in the US population 3 and in
… in aspects of heart failure and their potential as novel clinical and therapeutic biomarkers. We …

Insights into foundational therapies for heart failure with reduced ejection fraction

JJV McMurray, KF Docherty - Clinical Cardiology, 2022 - Wiley Online Library
… In this review, we discuss what is meant by “foundational” therapy for patients with heart failure
… offered by hospitalization for worsening heart failure to initiate and optimize foundational …

Cardiac energy metabolism in heart failure

GD Lopaschuk, QG Karwi, R Tian, AR Wende… - Circulation …, 2021 - Am Heart Assoc
… of the energy metabolic changes that occur in heart failure. This includes distinguishing the
… , as well as heart failure associated with diabetes (ie, diabetic cardiomyopathy). Although we …

Congestion in heart failure: a contemporary look at physiology, diagnosis and treatment

EM Boorsma, JM Ter Maaten, K Damman… - Nature reviews …, 2020 - nature.com
… with acute decompensated heart failure and is an important target for therapy. However, …
the outcomes of patients with acute decompensated heart failure. Although the majority of these …

[HTML][HTML] A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

S Fuloria, J Mehta, A Chandel, M Sekar… - Frontiers in …, 2022 - frontiersin.org
… longa, is well known for its therapeutic potential in numerous disorders. However, there is
a lack of literature on the therapeutic potential of C. longa in contrast to curcumin. Hence, the …