Medical therapies for heart failure with preserved ejection fraction

SE Kjeldsen, TG von Lueder, OA Smiseth… - …, 2020 - Am Heart Assoc
… -risk hypertension and heart failure with reduced ejection fraction, … in hypertension and heart
failure with reduced ejection … cardiovascular disease from hypertension to heart failure (HF). …

Abnormalities of Potassium in Heart Failure: JACC State-of-the-Art Review

JP Ferreira, J Butler, P Rossignol, B Pitt… - Journal of the American …, 2020 - jacc.org
… and hyperkalemia) in heart failure is common because of heart failure itself, related …
Hypokalemia is associated with excess morbidity and mortality in heart failure. The lower the K + …

Iron deficiency: a new target for patients with heart failure

C Rizzo, R Carbonara, R Ruggieri… - Frontiers in …, 2021 - frontiersin.org
… Iron deficiency (ID) is one of the most frequent comorbidities in patients with heart failure (HF).
ID is estimated to be present in up to 50% of outpatients and is a strong independent …

Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development

CR Ferraz, TT Carvalho, MF Manchope, NA Artero… - Molecules, 2020 - mdpi.com
… Thus, defining whether a flavonoid has therapeutic potential solely by its structure and
chemical groups with antioxidant potential is not adequate to take full advantage of plant …

[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?

A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
… This review provides evidence regarding the potential effects of ginger against SARS-CoV-2
infection and highlights its antiviral, anti-inflammatory, antioxidative, and …

Stimulation of soluble guanylyl cyclase (sGC) by riociguat attenuates heart failure and pathological cardiac remodelling

J Rüdebusch, A Benkner, N Nath… - British journal of …, 2022 - Wiley Online Library
… Accordingly, restoration of the NO–sGC–cGMP pathway is an attractive pharmacological target
for heart failure therapy… To test the therapeutic potential of riociguat, we first induced heart

Circulating heart failure biomarkers beyond natriuretic peptides: review from the Biomarker Study Group of the Heart Failure Association (HFA), European Society of …

WC Meijers, A Bayes‐Genis, A Mebazaa… - … of heart failure, 2021 - Wiley Online Library
… the management of patients with heart failure. Despite a large … management of patients with
heart failure. We discuss high-… Furthermore, we discuss potential implementation in clinical …

Cardiac xenotransplantation: a promising way to treat advanced heart failure

S Shu, J Ren, J Song - Heart Failure Reviews, 2022 - Springer
Heart failure is considered an epidemic disease in the modern world affecting … stage heart
failure; however, cardiac allotransplantation is limited by a severe global donor heart shortage […

Novel oxidative stress biomarkers with risk prognosis values in heart failure

ML Ng, X Ang, KY Yap, JJ Ng, ECH Goh, BBJ Khoo… - Biomedicines, 2023 - mdpi.com
… We also discussed potential biomarkers with therapeutic potential, and representative studies
are illustrated in Figure 2. Representative studies of the prognostic value of OS biomarkers …

Heart failure and atrial fibrillation: new concepts in pathophysiology, management, and future directions

G Tsigkas, A Apostolos, S Despotopoulos… - Heart Failure …, 2022 - Springer
… A bidirectional pathophysiological link connects heart failure and atrial fibrillation, creating a
… most of the established treatment measures for heart failure as well as rhythm or rate control …