… of the lack of mAbcb1 and mAbcg2 on morphine brain accumulation (around 8-fold higher
in … had no significant impact on the brain accumulation of morphine (Supplementary Fig. 3). …

… This study focused on the short-term analgesic effects after morphine administration, in which
morphine alone is mainly responsible for the analgesic effects. Accumulation of morphine-6…

… levels seem to increase upon repeated systemic exposure, we wanted to compare the
deposition of morphine in the retina to the brain. We chose to compare the retina to the …

… between morphine and zinc, manganese, chromium, cadmium, lead, fluoride, their impact
on neural pathways associated with addiction, and on antinociception and morphine tolerance …

… Accumulation of fluoride in the brain has been shown to cause neurodegenerative
changes in the striatum, motor cortex, cerebellum, and amygdala of rats [9,10]. Studies on the …

… significantly reduced the inhibitory phosphorylation of HMGCR, which might enhance
intracellular cholesterol accumulation. Little is known about the relationship between opioid …

… that the distribution of morphine to the brain followed a first-… , but not morphine, reduced μ
receptor (the main morphine … first to report the brain distribution of morphine, which can be …

… are very different from those of humans, 40 and it is difficult to … are similar to those in human
brains. Therefore, we established … inhibition of forskolin-stimulated cAMP accumulation: (1 − […

… A recent analysis of the neuroimaging data from two databases of human brains revealed
… The accumulation of MBP in the plasma of morphine-treated female mice suggests that …

… brain function. Finally, we provide extra cues as to how morphine further disorganizes gut-brain …
Accumulation of CD163 and CD206 alternative microglia could serve as a means to …