A DNA methylation atlas of normal human cell types

N Loyfer, J Magenheim, A Peretz, G Cann, J Bredno… - Nature, 2023 - nature.com
… as clinical diagnosis based on circulating cell-free DNA methylation. Methylation atlas of
human cell types To portray genome-wide DNA methylation across a variety of cell types, we …

Mitochondrial DNA methylation and human diseases

A Stoccoro, F Coppedè - International Journal of Molecular Sciences, 2021 - mdpi.com
… Epigenetics refers to heritable changes in gene regulation that are not due to changes in
the DNA sequence, including DNA methylation, histone modifications and non-coding RNA-…

DNA methylation methods: Global DNA methylation and methylomic analyses

S Li, TO Tollefsbol - Methods, 2021 - Elsevier
… These approaches hold promise for facilitating our comprehensive understanding of DNA
methylation patterns of any cells, tissues, or organisms in the context of growth, development, …

Evolution of DNA methylation in the human brain

H Jeong, I Mendizabal, S Berto, P Chatterjee… - Nature …, 2021 - nature.com
… the human brain. Here we have elucidated DNA methylation changes during recent human
brain … We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and …

DNA methylation in human sperm: a systematic review

F Åsenius, AF Danson, SJ Marzi - Human reproduction update, 2020 - academic.oup.com
… of cost-effective methods of interrogating DNA methylation, this premise has led to an … DNA
methylation landscape of human spermatozoa. However, how the human spermatozoal DNA

Universal DNA methylation age across mammalian tissues

AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li… - Nature aging, 2023 - nature.com
Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …

[HTML][HTML] DNA methylation: a historical perspective

AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
… rapidly growing number of base-resolution methylation maps. Despite this, several … of DNA
methylation patterns remain under investigation. Here, we review the field of DNA methylation

DNA methylation in solid tumors: functions and methods of detection

A Martisova, J Holcakova, N Izadi, R Sebuyoya… - International Journal of …, 2021 - mdpi.com
… For instance, decrease in DNA methylation of human pericentromeric repeat sequence
Satellite 2 (SAT2) is associated with accumulation of a large number of chromosome …

Universal DNA methylation age across mammalian tissues

AT Lu, Z Fei, A Haghani, TR Robeck, JA Zoller, CZ Li… - BioRxiv, 2021 - biorxiv.org
… From these methylation profiles, we … in humans, mutations that affect the somatotropic axis
in mice, and caloric restriction. We characterized specific cytosines, whose methylation levels …

Exposure to glyphosate and tetrachlorvinphos induces cytotoxicity and global DNA methylation in human cells

H Ergun, A Cayir - Toxicology and Industrial Health, 2021 - journals.sagepub.com
cells with higher concentrations of glyphosate and tetrachlorvinphos. Our results revealed
that DNA methylation … level of m 5 C DNA methylation methyltransferase. Finally, exposure to …