Renin cells, the kidney, and hypertension
MLS Sequeira-Lopez, RA Gomez - Circulation research, 2021 - Am Heart Assoc
… the memory of the renin phenotype and the intrinsic plasticity of renin cells to switch identity
to preserve homeostasis. Finally, we describe how permanent changes in renin cell fate lead …
to preserve homeostasis. Finally, we describe how permanent changes in renin cell fate lead …
(Pro) renin receptor in the kidney: function and significance
… Binding kinetics of renin and prorenin in rat vascular smooth muscle cells overexpressing
the human (pro)renin receptor. J Hypertens 25: 2441–2453, 2007. doi:10.1097/HJH.…
the human (pro)renin receptor. J Hypertens 25: 2441–2453, 2007. doi:10.1097/HJH.…
[HTML][HTML] The relationship of plasma renin, angiotensin, and aldosterone levels to blood pressure variability and target organ damage in children with essential …
Y Liu, Y Lin, MM Zhang, XH Li, YY Liu, J Zhao… - BMC Cardiovascular …, 2020 - Springer
… Of the 132 patients, 55 (41.7%) had target organ damage, … (58.3%) had no target organ
damage, including 61 males (79.2… plasma renin/angiotensin/aldosterone levels and target organ …
damage, including 61 males (79.2… plasma renin/angiotensin/aldosterone levels and target organ …
[HTML][HTML] A new perspective on the renin-angiotensin system
A Martyniak, PJ Tomasik - Diagnostics, 2022 - mdpi.com
… Human studies suggest that excess aldosterone has a direct pro-inflammatory and fibrotic
effect, contributing to target organ degradation, which manifests itself in the development of …
effect, contributing to target organ degradation, which manifests itself in the development of …
Renin–angiotensin system: Basic and clinical aspects—A general perspective
RAV Vargas, JMV Millán, EF Bonilla - Endocrinología, Diabetes y Nutrición …, 2022 - Elsevier
… The image illustrates the main organs and components of the renin–angiotensin system.
Similarly, it illustrates the elements that make up the classic RAS and the alternative RAS, …
Similarly, it illustrates the elements that make up the classic RAS and the alternative RAS, …
[HTML][HTML] Role of the central renin‑angiotensin system in hypertension
C Su, J Xue, C Ye, A Chen - … journal of molecular …, 2021 - spandidos-publications.com
… A disruption in the renin-angiotensin system (RAS), including the systemic and brain RAS, …
As a hormone, renin is secreted by granular cells in the juxtaglomerular apparatus of kidneys (…
As a hormone, renin is secreted by granular cells in the juxtaglomerular apparatus of kidneys (…
[HTML][HTML] Targeting the renin–angiotensin–aldosterone system to prevent hypertension and kidney disease of developmental origins
… As the RAAS cascade starts with renin, it raises the question of can we block the RAAS at
its point of activation (ie, renin) to prevent renal programming? The first selective renin inhibitor…
its point of activation (ie, renin) to prevent renal programming? The first selective renin inhibitor…
Renin-angiotensin system and inflammation update
E Cantero-Navarro, B Fernandez-Fernandez… - Molecular and cellular …, 2021 - Elsevier
… The most classical view of the renin-angiotensin system (RAS) emphasizes its role as an
endocrine regulator of sodium balance and blood pressure. Renin mediates angiotensin I …
endocrine regulator of sodium balance and blood pressure. Renin mediates angiotensin I …
[HTML][HTML] Molecular interactions of arterial hypertension in its target organs
J Kućmierz, W Frąk, E Młynarska, B Franczyk… - International Journal of …, 2021 - mdpi.com
… in pathogenesis of AH and hypertension-related target organ damage. In our paper, we would
… renin-angiotensin-aldosterone system and oxidative stress in hypertensive induced organ …
… renin-angiotensin-aldosterone system and oxidative stress in hypertensive induced organ …
[HTML][HTML] Brain renin–angiotensin system as novel and potential therapeutic target for Alzheimer's disease
R Loera-Valencia, F Eroli, S Garcia-Ptacek… - International journal of …, 2021 - mdpi.com
… of renin and renin-like activity in neuronal cells and the brain in general. Renin was … from
rats [7] and immunohistochemical methods show the renin-like activity in rat and mouse brains […
rats [7] and immunohistochemical methods show the renin-like activity in rat and mouse brains […