Sperm DNA integrity status is associated with DNA methylation signatures of imprinted genes and non-imprinted genes
B Song, C Wang, Y Chen, G Li, Y Gao, F Zhu… - … and Genetics, 2021 - Springer
… cases with impaired sperm DNA integrity). We detected the methylation status of 257 CpG
sites among two imprinted genes (H19 and SNRPN) and four non-imprinted genes related to …
sites among two imprinted genes (H19 and SNRPN) and four non-imprinted genes related to …
Male infertility is associated with differential DNA methylation signatures of the imprinted gene GNAS and the non-imprinted gene CEP41
… Methylation anomalies of the H19, IGF2, GNAS, GNASAS, and MEST imprinted genes have
… -imprinted gene CEP41 are highly expressed in the testis, their effects on male fertility are …
… -imprinted gene CEP41 are highly expressed in the testis, their effects on male fertility are …
Paternal exposure to arsenic and sperm DNA methylation of imprinting gene Meg3 in reproductive-aged men
Z Lu, C Zhao, J Yang, Y Ma, M Qiang - Environmental geochemistry and …, 2023 - Springer
… the sperm DNA methylation level of imprinting gene Meg3 was found in this study, implicating
Meg3 is the most sensitive to the environmental arsenic exposure. Recently, substantial …
Meg3 is the most sensitive to the environmental arsenic exposure. Recently, substantial …
Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes
S Di Persio, E Leitão, M Wöste, T Tekath, JF Cremers… - Clinical …, 2021 - Springer
… putative enhancer sites and imprinted loci. Our comparison of control sperm and testicular
germ cell methylomes revealed slightly lower mean methylation levels in testicular germ cells. …
germ cell methylomes revealed slightly lower mean methylation levels in testicular germ cells. …
Inheritance of paternal lifestyles and exposures through sperm DNA methylation
KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
… blood–testis … imprinted genes, H19 DMR and IG-DMR in human sperm 83 and tobacco
smoking has being linked to increased DNA methylation levels at the DLK1 DMR in men’s sperm …
smoking has being linked to increased DNA methylation levels at the DLK1 DMR in men’s sperm …
Sperm epigenetics and male infertility: unraveling the molecular puzzle
M Hosseini, A Khalafiyan, M Zare, H Karimzadeh… - Human Genomics, 2024 - Springer
… of the H19 gene has been observed in the testicular sperm of … sperm DNA methylation
aberrations of imprinted genes revealed considerably elevated methylation levels of these genes …
aberrations of imprinted genes revealed considerably elevated methylation levels of these genes …
Role of genetics and epigenetics in male infertility
S Gunes, SC Esteves - Andrologia, 2021 - Wiley Online Library
… of imprinting genes and developmental genes have been … sperm retrieval success rates
than conventional testicular … comparing sperm DNA methylation aberrations of imprinted genes …
than conventional testicular … comparing sperm DNA methylation aberrations of imprinted genes …
Epigenetic modifications at DMRs of imprinting genes in sperm of type 2 diabetic men
M Jazayeri, P Eftekhari-Yazdi, MAS Gilani, M Sharafi… - Zygote, 2022 - cambridge.org
… imprinting genes in sperm and semen quality indices in T2DM patients. For this purpose,
sperm … In the next step, methylation of DMRs of the three imprinting genes H19, MEST and …
sperm … In the next step, methylation of DMRs of the three imprinting genes H19, MEST and …
Effects of intrauterine exposure to 2, 3′, 4, 4′, 5‐pentachlorobiphenyl on the reproductive system and sperm epigenetic imprinting of male offspring
QL He, TQ Lyu, YT Zhang, HQ Wang… - Journal of applied …, 2020 - Wiley Online Library
… of the mouse imprinted genes in offspring sperm, we further … in Dnmts in testicular tissues
can affect sperm quality. … abnormal phenotypes of the sperm and testicles in male offspring and …
can affect sperm quality. … abnormal phenotypes of the sperm and testicles in male offspring and …
Sperm DNA methylome abnormalities occur both pre-and post-treatment in men with Hodgkin disease and testicular cancer
… , imprinted gene methylation was not affected in the sperm of … of human testicular cancer
treatment regimens (BEP) on sperm … Similar to our human studies, imprinted gene methylation …
treatment regimens (BEP) on sperm … Similar to our human studies, imprinted gene methylation …
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