Interplay between cellular and molecular mechanisms underlying inflammatory bowel diseases development—a focus on ulcerative colitis

I Samoilă, S Dinescu, M Costache - Cells, 2020 - mdpi.com
Inflammatory bowel diseases (IBD) are defined by the continuous inflammation of the …
lower response to pathogens interaction and a higher chance of developing inflammation [77,78]. …

[HTML][HTML] Possible synergy effect of hydrogen sulfide and acetate produced by sulfate-reducing bacteria on inflammatory bowel disease development

I Kushkevych, D Dordević, M Vítězová - Journal of Advanced Research, 2021 - Elsevier
… correlations between illness development and hydrogen … the connection with inflammatory
bowel diseases and sulfate-… with the development of inflammatory bowel disease (IBD) …

The microbiome and inflammatory bowel disease

KL Glassner, BP Abraham, EMM Quigley - Journal of Allergy and Clinical …, 2020 - Elsevier
… The disease is thought to develop as a result of interactions between … in the development
of intestinal inflammation. Thus a germ-free environment prevents the development of colitis in …

Serum biomarkers identify patients who will develop inflammatory bowel diseases up to 5 years before diagnosis

J Torres, F Petralia, T Sato, P Wang, SE Telesco… - Gastroenterology, 2020 - Elsevier
… Biomarkers are needed to identify patients at risk for development of inflammatory bowel
diseases. We aimed to identify serum biomarkers of Crohn’s disease and ulcerative colitis that …

Antibiotic use and the development of inflammatory bowel disease: a national case-control study in Sweden

LH Nguyen, AK Örtqvist, Y Cao, TG Simon… - The lancet …, 2020 - thelancet.com
Background Use of antibiotics in early life has been linked with childhood inflammatory bowel
disease (IBD), but data for adults are mixed, and based on smaller investigations that did …

Pathway paradigms revealed from the genetics of inflammatory bowel disease

DB Graham, RJ Xavier - Nature, 2020 - nature.com
Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and amplified
… This core set of pathways represents vulnerabilities to disease development that suggest …

Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
… For example, germ-free mice do not develop colitis, and inflammatory changes can be induced
… to colitis development, antibiotic administration early in life increased the risk of colitis [7]. …

An update of research animal models of inflammatory bowel disease

Z Baydi, Y Limami, L Khalki, N Zaid… - The Scientific World …, 2021 - Wiley Online Library
… Mechanisms of inflammatory bowel disease. The intestine shelters a large diversity of … barrier
and lead to the development of inflammatory bowel disease. The stimulation of the mucosal …

Changing global epidemiology of inflammatory bowel diseases: sustaining health care delivery into the 21st century

AN Ananthakrishnan, GG Kaplan, SC Ng - Clinical Gastroenterology and …, 2020 - Elsevier
… susceptibility, and environmental exposures, will help to better understand the very early
risk factors (as far back as during pregnancy) for disease development and help develop

Colorectal cancer in inflammatory bowel disease: mechanisms and management

SC Shah, SH Itzkowitz - Gastroenterology, 2022 - Elsevier
… Patients with inflammatory bowel disease (IBD) are at increased risk of developing
colorectal cancer (CRC), despite decreases in CRC incidence in recent years. Chronic …