Traumatic brain injury: progress and challenges in prevention, clinical care, and research

AIR Maas, DK Menon, GT Manley, M Abrams… - The Lancet …, 2022 - thelancet.com
… Traumatic brain injury (TBI) has the highest incidence of all common neurological disorders,
… under the umbrella of the International Traumatic Brain Injury Research (InTBIR) initiative, …

Clinical relevance of behavior testing in animal models of traumatic brain injury

SR Shultz, SJ McDonald, F Corrigan… - Journal of …, 2020 - liebertpub.com
… that allow for assessment of clinically relevant behavioral outcomes. Note that this section
… of behavioral studies that have been conducted in the many different preclinical brain injury

Effects of Repetitive Mild Traumatic Brain Injury on Corticotropin-Releasing Factor Modulation of Lateral Habenula Excitability and Motivated Behavior

WJ Flerlage, SC Simmons, EH Thomas… - Journal of …, 2024 - liebertpub.com
… closed injury mouse model of mTBI which induces behavioral deficits in motivational self-care
grooming in sucrose splash test 39 and social interaction test 40 as well as persistent LHb …

Protective effects of early exercise on neuroinflammation, and neurotoxicity associated by traumatic brain injury: A behavioral and neurochemical approach

F Rafie, M Khaksari, S Amiresmaili… - International Journal …, 2024 - Taylor & Francis
… for seven days) was more effective than late exercise (9 days post-injury) in the improvement
of recognition memory and the prevention of brain injury expansion in mice [Citation25]. In …

[HTML][HTML] A brain-centric model of suicidal behavior

JJ Mann, MM Rizk - American journal of psychiatry, 2020 - Am Psychiatric Assoc
behavior, and it often does not progress to suicidal behavior (15). Suicide prevention
measures might prevent the transitioning from ideation to behavior if we understood the factors …

Management of traumatic brain injury: from present to future

R Crupi, M Cordaro, S Cuzzocrea, D Impellizzeri - Antioxidants, 2020 - mdpi.com
TBI (traumatic brain injury) is a major cause of death among youth in industrialized societies.
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …

Mental health consequences of traumatic brain injury

JR Howlett, LD Nelson, MB Stein - Biological psychiatry, 2022 - Elsevier
… , affective, and behavioral sequelae of injuries across the severity … behavioral sequelae.
The nature and etiology of mental health manifestations of TBI (including a combination of brain

From biomechanics to pathology: predicting axonal injury from patterns of strain after traumatic brain injury

CK Donat, M Yanez Lopez, M Sastre, N Baxan… - Brain, 2021 - academic.oup.com
… milliseconds after injury are important factors in determining patterns of glial and axonal
injury and serve as experimental validators of our computational model of traumatic brain injury. …

Epidemiology of chronic effects of traumatic brain injury

J Haarbauer-Krupa, MJ Pugh, EM Prager… - Journal of …, 2021 - liebertpub.com
… in cognition, behavior, and mental health 39,42 ; these deficits appear to be independent
of the injury mechanism, duration of time post-injury, and age at the time of injury. Emerging …

Traumatic brain injury: an overview of epidemiology, pathophysiology, and medical management

A Capizzi, J Woo, M Verduzco-Gutierrez - Medical Clinics, 2020 - medical.theclinics.com
Prevention (CDC), a TBI is caused by a bump, blow, or jolt to the head, or a penetrating head
injury that disrupts the normal function of the brain. … to identify specific behaviors to create a …