Intranasal oxytocin alleviates comorbid depressive symptoms in neuropathic pain via elevating hippocampal BDNF production in both female and male mice

R Liu, D Sun, X Xing, Q Chen, B Lu, B Meng, H Yuan… - …, 2024 - Elsevier
… Because of the advantage of intranasal delivery of oxytocin … effect of intranasal application
of oxytocin on neuropathic pain and … the effect of intranasal oxytocin on neuropathic pain and …

Intranasal administration for pain: oxytocin and other polypeptides

VN Bharadwaj, AZ Tzabazis, M Klukinov, NA Manering… - Pharmaceutics, 2021 - mdpi.com
pain, but not in men [61]. Similarly, a recent study on the perception of wound pain showed
that intranasal oxytocin reduced wound pain in … nerve—and have shown that nasal oxytocin

Evaluating the efficacy of intranasal oxytocin on pain and function among individuals who experience chronic pain: a protocol for a multisite, placebo-controlled …

JA Rash, TS Campbell, L Cooper, D Flusk… - BMJ open, 2021 - bmjopen.bmj.com
… with primary neuropathic painpain arising as a direct consequence of a lesion or disease
affecting the central or peripheral nervous system46—will be eligible. Neuropathic pain will …

Preliminary results from a randomized, controlled, cross-over trial of intrathecal oxytocin for neuropathic pain

JC Eisenach, RS Curry, TT Houle - Pain Medicine, 2023 - academic.oup.com
… administration at dose orders of magnitude greater than are tested in humans, and human
studies, which typically utilize intranasal oxytocin administration, are as likely to show no …

Up‐regulation of oxytocin receptors on peripheral sensory neurons mediates analgesia in chemotherapy‐induced neuropathic pain

L Li, P Li, J Guo, Y Wu, Q Zeng, N Li… - British Journal of …, 2023 - Wiley Online Library
… The activation of oxytocin receptor (OXTR) mediated the antinociceptive effects of
intravenous injection of oxytocin (OXT) on paclitaxel (PTX)-induced neuropathic pain. (a) The …

Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations

DC Yeomans, LR Hanson, DS Carson… - Translational …, 2021 - nature.com
… concentrations of oxytocin observed along the trigeminal nerve and pons, medulla, and
cerebellum in the present study appear to also suggest a route along the trigeminal nerve that …

Intranasal oxytocin as a treatment for chronic pelvic pain: A randomized controlled feasibility study

MJ Flynn, TS Campbell, M Robert… - … of Gynecology & …, 2021 - Wiley Online Library
… , interstitial cystitis, functional bowel disorder, fibromyalgia, neuropathic pain, or lower
abdominal pain with no evidence of pelvic floor myalgia; and/or (8) only experienced …

[HTML][HTML] Protocol: Evaluating the efficacy of intranasal oxytocin on pain and function among individuals who experience chronic pain: a protocol for a multisite, placebo …

JA Rash, TS Campbell, L Cooper, D Flusk… - BMJ Open, 2021 - ncbi.nlm.nih.gov
… with primary neuropathic painpain arising as a direct consequence of a lesion or disease
affecting the central or peripheral nervous system 46 —will be eligible. Neuropathic pain will …

Intrathecal oxytocin for neuropathic pain: A randomized, controlled, cross-over trial

JC Eisenach, RS Curry, TT Houle - medRxiv, 2022 - medrxiv.org
… administration at dose orders of magnitude greater than are tested in humans, and human
studies, which typically utilize intranasal oxytocin administration, are as likely to show no …

[HTML][HTML] An investigation on the role of oxytocin in chronic neuropathic pain in a Wistar rat model

M de Kock, S Chetty, AS Isa, L Qulu-Appiah - Neurobiology of Pain, 2024 - Elsevier
… Animals that received Paclitaxel and treated with oxytocin also … the hypothesis that intranasally
administered oxytocin may … on chronic pain management using intranasal oxytocin (Wang…