Iron pathways and iron chelation approaches in viral, microbial, and fungal infections
R Chhabra, A Saha, A Chamani, N Schneider, R Shah… - Pharmaceuticals, 2020 - mdpi.com
… development of infections. This review will serve to assimilate findings regarding iron and …
, find whether treating infections mediated by such organisms via iron chelation approaches …
, find whether treating infections mediated by such organisms via iron chelation approaches …
[HTML][HTML] Iron in infection and immunity
M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
… , autoimmune disease or malignancy however, sequesters iron not only from infectious …
iron metabolism and immunity, focusing on host defense against relevant infections and on …
iron metabolism and immunity, focusing on host defense against relevant infections and on …
[HTML][HTML] Iron in immune cell function and host defense
D Haschka, A Hoffmann, G Weiss - Seminars in Cell & Developmental …, 2021 - Elsevier
… against microbial infections and help to limit bacterial multiplication, at least partly by binding
divalent metals like iron and deprive the pathogen of iron. Lipocalin 2 (Lcn2) can bind iron-…
divalent metals like iron and deprive the pathogen of iron. Lipocalin 2 (Lcn2) can bind iron-…
The battle for iron in enteric infections
A Sousa Gerós, A Simmons, H Drakesmith… - …, 2020 - Wiley Online Library
… inter-kingdom fight for iron is never-… iron homeostasis in the gastrointestinal tract. We first
detail how mammalian systemic and cellular iron homeostasis influences gastrointestinal iron …
detail how mammalian systemic and cellular iron homeostasis influences gastrointestinal iron …
Iron at the host-microbe interface
… As such, siderophore immunization might be a promising approach to limit microbial iron
acquisition during infection. To this end, immunization against yersiniabactin and aerobactin in …
acquisition during infection. To this end, immunization against yersiniabactin and aerobactin in …
Host-microbial battle for iron: new opportunities to combat infection?
E Wine - Gastroenterology, 2024 - Elsevier
… Iron is essential for cellular function, especially with rapid growth during bacterial infection.
However, as intracellular iron is toxic, pathogens aim to get and hold onto iron while avoiding …
However, as intracellular iron is toxic, pathogens aim to get and hold onto iron while avoiding …
The impact of metal availability on immune function during infection
AJ Monteith, EP Skaar - Trends in Endocrinology & Metabolism, 2021 - cell.com
… During infection, invading bacterial pathogens must acquire essential metals, such as zinc,
manganese, iron… during infection. How the host manipulates nutrient metal availability during …
manganese, iron… during infection. How the host manipulates nutrient metal availability during …
Baseline iron status and presence of anaemia determine the course of systemic Salmonella infection following oral iron supplementation in mice
A Hoffmann, D Haschka, LV de Souza, P Tymoszuk… - …, 2021 - thelancet.com
… for bacterial infections during oral iron supplementation … iron supplementation in mice that
are either iron depleted or have a normal iron availability and studied the course of infection as …
are either iron depleted or have a normal iron availability and studied the course of infection as …
[HTML][HTML] Role of reactive oxygen species and iron in host defense against infection
KB Dickson, J Zhou - Frontiers in Bioscience-Landmark, 2020 - imrpress.com
… of bloodstream infections in those with very low iron levels (… infection susceptibility may be
dependent on the level of iron … , with infection risk being increased from either extreme of iron …
dependent on the level of iron … , with infection risk being increased from either extreme of iron …
Microbial metabolite signaling is required for systemic iron homeostasis
… an iron-dependent mechanism that inhibits host iron transport and storage. Using a high-throughput
screen of microbial … factor of intestinal iron absorption and increase the iron-storage …
screen of microbial … factor of intestinal iron absorption and increase the iron-storage …
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