Bevacizumab plus erlotinib versus erlotinib alone in Japanese patients with advanced, metastatic, EGFR-mutant non-small-cell lung cancer (NEJ026): overall survival …

Y Kawashima, T Fukuhara, H Saito… - The Lancet …, 2022 - thelancet.com
… The JO25567 study was a randomised, multicentre, phase 2 trial that compared
bevacizumab–erlotinib with erlotinib alone as first-line treatments in 154 Japanese patients with …

[HTML][HTML] Real-world effectiveness and safety of nivolumab in patients with non-small cell lung cancer: A multicenter retrospective observational study in Japan

R Morita, K Okishio, J Shimizu, H Saito, H Sakai… - Lung Cancer, 2020 - Elsevier
Japanese patients with NSCLC who received nivolumab were analyzed retrospectively.
Patients who had started nivolumab treatment between April 2016 and December 2016 were …

[HTML][HTML] Differences in molecular epidemiology of lung cancer among ethnicities (Asian vs. Caucasian)

M Izumi, T Suzumura, K Ogawa… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
patients with lung adenocarcinoma, this research revealed KRAS mutations in 4.3% of
Japanese patients … less frequent in Japanese patients than in Caucasian patients, even among …

Clinical impacts of EGFR mutation status: analysis of 5780 surgically resected lung cancer cases

…, Japanese Joint Committee of Lung Cancer … - The Annals of thoracic …, 2021 - Elsevier
… 13,951 patients with nonsquamous non-small cell lung cancer included in this study, 5780
patients (… in a large cohort of Japanese patients with surgically treated lung adenocarcinoma …

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised …

H Saji, M Okada, M Tsuboi, R Nakajima, K Suzuki… - The Lancet, 2022 - thelancet.com
… -stage lung cancer is only indicated for selected patients with … 90s in Japan, the early detection
of small-sized early lung … is a highly malignant disease, according to our results, patients

Low-dose erlotinib treatment in elderly or frail patients with EGFR mutation–positive non–small cell lung cancer: A multicenter phase 2 trial

S Miyamoto, K Azuma, H Ishii, A Bessho… - JAMA …, 2020 - jamanetwork.com
… frail patients from 21 Japanese institutions after meeting the inclusion criteria.
Chemotherapy-naive patients withEGFR-activating mutation–positive non–small cell lung cancer

Final progression-free survival results from the J-ALEX study of alectinib versus crizotinib in ALK-positive non-small-cell lung cancer

K Nakagawa, T Hida, H Nokihara, M Morise, K Azuma… - Lung Cancer, 2020 - Elsevier
… The J-ALEX study compared the efficacy and safety of alectinib with crizotinib in Japanese
patients with advanced ALK-positive non-small-cell lung cancer (NSCLC). Superiority in …

Brigatinib in Japanese patients with tyrosine kinase inhibitor-naive ALK-positive non-small cell lung cancer: first results from the phase 2 J-ALTA study

S Sugawara, M Kondo, T Yokoyama, T Kumagai… - International Journal of …, 2022 - Springer
… This study is the first prospective clinical trial in Japanese patients to evaluate brigatinib
efficacy and safety in patients with ALK-positive NSCLC who had not received ALK TKI treatment…

… pemetrexed followed by maintenance pemetrexed with docetaxel monotherapy in elderly patients with advanced nonsquamous non–small cell lung cancer: a phase 3 …

I Okamoto, H Nokihara, S Nomura, S Niho… - JAMA …, 2020 - jamanetwork.com
… Our Japan-specific trial may limit the generalizability of the results, since all enrolled
participants are Japanese patients with NSCLC who usually show better survival than Western …

A single-arm study of sublobar resection for ground-glass opacity dominant peripheral lung cancer

…, H Asamura, West Japan Oncology Group… - The Journal of thoracic …, 2022 - Elsevier
… To select lung cancer that has no nodal involvement or lymphovascular invasion, the Japan
… The study defined radiologic noninvasive lung cancer as lung cancer 2 cm or less in size …