… Pluripotency maintenance and lineage differentiation are two major characteristics of human
embryonic and induced pluripotent … of lncRNA functions in pluripotency maintenance/exit …

… In this study, we showed that tissue mechanics dictate the lineage specification and
differentiation of pluripotent stem cells. Specifically, a substrate with a stiffness similar to the liver …

Embryonic Stem cells are widely studied to elucidate the disease and developmental
processes because of their capability to differentiate into cells of any lineage, Pervasive …

… The Role of LncRNA in Stem Cell Pluripotency Stem cell pluripotency and differentiation
are regulated by a multilayered and complicated network, including lncRNA. Since PSCs hold …

… and the expression of the nearby pluripotency regulator ZFP281. Through these regulatory
events, Platr22 contributes to pluripotency maintenance and proper differentiation of mESCs. …

Although many long non-coding RNAs (lncRNAs) exhibit lineage-specific expression, the
vast majority remain functionally uncharacterized in the context of development. Here, we …

The generation of induced pluripotent stem cells through somatic cell reprogramming
requires a global reorganization of cellular functions. This reorganization occurs in a multi-phased …

… LincRNA-EPS has a role in the erythroid differentiation as its suppression has blocked
erythroid differentiation and enhanced apoptosis. This lncRNA has been shown to suppress …

… The identification of stem cell-specific lincRNAs and their interacting partners will deepen
our understanding of the maintenance of stem cell pluripotency. We identified a lincRNA, LincQ…

… embryonic lncRNA, pluripotency-associated transcript 4 (Platr4), directly influences the
specification of cardiacmesoderm-lineage differentiation. We show that Platr4 acts as a molecular …