Non-cell-autonomous control of gastruloid development by the lncRNA T-UCstem1 through DKK1-dependent modulation of WNT signalling

A Coppola, F Amoroso, F Saracino, G Andolfi, E Sozzi… - bioRxiv, 2024 - biorxiv.org
… expression of pluripotency and differentiation markers points to a key role of T-UCstem1
in 34 … examined the expression profiles of pluripotency and differentiation markers in 5-day-old …

[HTML][HTML] The Expression and Function of lincRNA-154324 and the Adjoining Protein-Coding Gene vmp1 in the Caudal Fin Regeneration of Zebrafish

J Li, W Wen, S Zhang, C Zhou, Y Feng, X Li - International Journal of …, 2022 - mdpi.com
… verify the expression of lincRNA-154324 after knockout, we conducted a WISH
experiment and the results showed that the expression of lincRNA-154324 in the lincRNA-154324-cas9 …

[HTML][HTML] Enhancer RNA lnc-CES1-1 inhibits decidual cell migration by interacting with RNA-binding protein FUS and activating PPARγ in URPL

Z Huang, H Yu, G Du, L Han, X Huang, D Wu… - … Therapy-Nucleic Acids, 2021 - cell.com
Unexplained recurrent pregnancy loss (URPL) is a significant reproductive health issue,
affecting approximately 5% of pregnancies. Enhancer RNAs (eRNAs) have been reported to …

Long noncoding RNA lnc-NAP sponges mmu-miR-139-5p to modulate Nanog functions in mouse ESCs and embryos

D Xie, M Tong, B Xia, G Feng, L Wang, A Li, G Luo… - RNA biology, 2021 - Taylor & Francis
… 0.05, grey dots represent genes showing no significant difference. (D) Expression heatmap
of marker genes for pluripotency and lineage differentiation in control ESCs and lnc-NAP KD …

[HTML][HTML] Comprehensive transcriptomic analysis of long non-coding RNAs in bovine ovarian follicles and early embryos

P Wang, ÉR Paquet, C Robert - Plos one, 2023 - journals.plos.org
… Based on proximity to nearby protein-coding genes, lncRNAs were subdivided into 5,272
intergenic (lincRNAs, 68%) and 2,452 genic lncRNAs (32%) probes. LincRNAs were further …

Long noncoding RNA expression profiling during the neuronal differentiation of glial precursor cells from rat dorsal root ganglia

Y Dai, W Ma, T Zhang, J Yang, C Zang, K Liu… - Biotechnology and …, 2020 - Springer
… Our results demonstrated significant differences in gene architecture and expression among
… (2011) lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature. 477: …

[HTML][HTML] Estimating residual undifferentiated cells in human chemically induced pluripotent stem cell derived islets using lncRNA as biomarkers

Y Wu, Z Zhang, S Wu, Z Chen, Y Pu - Scientific Reports, 2023 - nature.com
Human pluripotent stem cells (hPSCs) can generate insulin-producing beta cells for diabetes
treatment, but residual undifferentiated cells may cause tumors. We developed a highly …

[HTML][HTML] Long non-coding RNAs RN7SK and GAS5 regulate macrophage polarization and innate immune responses

I Ahmad, A Valverde, RA Naqvi, AR Naqvi - Frontiers in Immunology, 2020 - frontiersin.org
… M2 macrophage differentiation and addressed whether their differential expression regulates
… Based on differential expression and further knockdown studies, our results divulges the …

[HTML][HTML] Linc-ROR facilitates progression and angiogenesis of hepatocellular carcinoma by modulating DEPDC1 expression

C Tian, M Abudoureyimu, X Lin, X Chu, R Wang - Cell death & disease, 2021 - nature.com
LincRNA regulator of reprogramming (Linc-ROR) was first identified as a regulator for the
reprogramming of differentiated cells to induce pluripotent stem cells in humans. Knockdown of …

Role of long non-coding RNAs (LncRNAs) in multiple sclerosis: a brief review

E Taghizadeh, F Taheri, MM Samadian… - Neurological …, 2020 - Springer
… of lincRNA expression and immune cell differentiation, development, and activation [1]. …
Researchers demonstrated that as a co-activator of NF-kB, lincRNA-Cox2 acts as a modulator of …