… by which oocytes can sense and respond to stress are not … due to lipotoxicity, oxidative
stress, and heat stress on oocyte … mechanisms in whole cumulus-oocyte complexes (COCs) can …

… protein responses and redox regulation increase in these oocytes [18]. In this model, alteration
in … Collection of bovine cumulus oocyte complexes (COCs) from slaughterhouse ovaries …

… SUMMARY ANSWER Surviving, morphologically normal blastocysts derived from bovine
oocytes that matured under lipotoxic conditions exhibit long-lasting cellular dysfunction at the …

… oocyte in phospholipids and cholesterol during maturation, and significant changes of FA
composition and related pathways in response to lipid modulators endorse the role of oocyte …

… and cumulus cells respond and cooperate with oocytes when … Compared to immature
cumulus–oocyte complexes (COCs), … in cells and decrease the lipotoxicity of NEFA to the oocyte. …

… This may imply that MT biogenesis is stimulated, mostly as a response to MT damage. …
Bovine cumulus-oocyte complexes and embryos were exposed to control (CONT), solvent …

… oocyte developmental competence. These cells are physically and metabolically linked with
an oocyte and form the cumulus-oocyte complex … in cell behavior and response. It is the part …

… This suggests that ED is maintained by complex molecular mechanisms in response to
metabolic changes (eg amino acid concentration and composition of the uterine fluid). …

… be mainly caused by lipotoxicity responses that promote ER … in ovarian follicular cells
which critically support the oocyte. … function, lipotoxicity in the cumulus oocyte complex is …

… , oxidative stress and ER stress responses in mouse oocytes and their effects on early …
Oviducts were collected from superovulated mice and oocyte–cumulus complexes (COCs) …