Correlates of malaria vaccine efficacy
DI Stanisic, MBB McCall - Expert Review of Vaccines, 2021 - Taylor & Francis
… efficacy against controlled human malaria infections (CHMI) and against naturally acquired
infections. Expert Opinion: Effective vaccination … disappointing efficacy of malaria vaccine …
infections. Expert Opinion: Effective vaccination … disappointing efficacy of malaria vaccine …
Malaria vaccines: progress to date
DI Stanisic, MF Good - BioDrugs, 2023 - Springer
… malaria vaccine and was shown to have modest efficacy … malaria vaccine that is able to
induce long-lasting protective … factors including the complexity of the malaria parasite’s life-cycle, …
induce long-lasting protective … factors including the complexity of the malaria parasite’s life-cycle, …
[HTML][HTML] … of humoral immune responses to the C-terminus of the circumsporozoite protein is associated with protective efficacy induced by the RTS, S malaria vaccine
S Chaudhury, RS MacGill, AM Early, JS Bolton… - Vaccine, 2021 - Elsevier
… Vaccines using a single allele may have lower efficacy … the efficacy of the CSP-based RTS,S
malaria vaccine may be … falciparum CSP alleles that diverge from the 3D7 vaccine allele, …
malaria vaccine may be … falciparum CSP alleles that diverge from the 3D7 vaccine allele, …
Malaria vaccines: a new era of prevention and control
… that prioritizes malaria vaccine … vaccines might improve upon the protective efficacy of RTS,S
or R21 for children, or address the wider malaria scourge by preventing pregnancy malaria, …
or R21 for children, or address the wider malaria scourge by preventing pregnancy malaria, …
Seasonal malaria vaccination with or without seasonal malaria chemoprevention
D Chandramohan, I Zongo, I Sagara… - … England Journal of …, 2021 - Mass Medical Soc
… The protective efficacy of the combination as compared with the vaccine alone against these
outcomes was 59.6% (95% CI, 54.7 to 64.0), 70.6% (95% CI, 42.3 to 85.0), and 75.3% (95% …
outcomes was 59.6% (95% CI, 54.7 to 64.0), 70.6% (95% CI, 42.3 to 85.0), and 75.3% (95% …
The effect of dosage on the protective efficacy of whole-sporozoite formulations for immunization against malaria
D Moita, C Rôla, H Nunes-Cabaço, G Nogueira… - npj Vaccines, 2023 - nature.com
… is an important determinant of the protective efficacy of different WSpz formulations 15,16,17
. In this study we compared the protective efficacy afforded by immunization of mice with …
. In this study we compared the protective efficacy afforded by immunization of mice with …
Randomized clinical trial to assess the protective efficacy of a Plasmodium vivax CS synthetic vaccine
M Arévalo-Herrera, X Gaitán, M Larmat-Delgado… - Nature …, 2022 - nature.com
… most advanced malaria vaccine candidate with a mean efficacy of ~… malaria vaccine among
children in sub-Saharan Africa and other regions with moderate to high P. falciparum malaria …
children in sub-Saharan Africa and other regions with moderate to high P. falciparum malaria …
Malaria vaccines since 2000: progress, priorities, products
PE Duffy, J Patrick Gorres - npj Vaccines, 2020 - nature.com
… Protective efficacy of PEV was first demonstrated in a human in the 1970s using radiation-attenuated
WSV delivered through hundreds of mosquito bites; the vaccinee was protected …
WSV delivered through hundreds of mosquito bites; the vaccinee was protected …
[HTML][HTML] Safety and efficacy of malaria vaccine candidate R21/Matrix-M in African children: a multicentre, double-blind, randomised, phase 3 trial
MS Datoo, A Dicko, H Tinto, JB Ouédraogo… - The Lancet, 2024 - thelancet.com
… that a new malaria vaccine, R21/Matrix-M, had over 75% efficacy against clinical malaria with
… Here, we report on safety and efficacy of the vaccine in a phase 3 trial enrolling over 4800 …
… Here, we report on safety and efficacy of the vaccine in a phase 3 trial enrolling over 4800 …
[HTML][HTML] Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled …
… to the Malaria Vaccine Technology Roadmap, WHO called for the development of malaria
vaccine candidates with a protective efficacy of at least 75% against clinical malaria by 2030, …
vaccine candidates with a protective efficacy of at least 75% against clinical malaria by 2030, …
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