microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
… , and developed a battery of viral and nonviral delivery … are a limited number of
microRNA-based applications that have … into viable microRNA-based clinical tools for cancer

A comprehensive review of cancer MicroRNA therapeutic delivery strategies

A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
… significant hurdles in therapeutic miRNA usage are the stability and the delivery system. In
… of therapeutic miRNA delivery systems that includes virus-based delivery, non-viral delivery (…

Challenges identifying efficacious miRNA therapeutics for cancer

M Segal, FJ Slack - Expert opinion on drug discovery, 2020 - Taylor & Francis
miRNA therapeutics will have a major part in cancer therapy in the future. Specifically,
personalized cancer medicine can be accomplished by constructing the unique miRNA mimic or …

Recent advances in miRNA delivery systems

I Dasgupta, A Chatterjee - Methods and protocols, 2021 - mdpi.com
… Nevertheless, RV-mediated miRNA delivery has been shown to be promising in regenerative
medicine. For example, heightened expression of miR-138 in murine embryonic fibroblasts …

miRacle of microRNA-driven cancer nanotherapeutics

G Kara, B Arun, GA Calin, B Ozpolat - Cancers, 2022 - mdpi.com
miRNA delivery. The aim of the present review is to provide insights into the strategies for
miRNA-based therapeutics in cancer, … studies that have used nanoparticles for miRNA delivery. …

Strategies to modulate microRNA functions for the treatment of cancer or organ injury

TJ Lee, X Yuan, K Kerr, JY Yoo, DH Kim, B Kaur… - Pharmacological …, 2020 - ASPET
… inhibitors and highlights current progress in miRNA-… in miRNA delivery, we believe that
additional therapeutic approaches to modulate miRNA function will soon enter routine medical

Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments

KKW To, W Fong, CWS Tong, M Wu… - Expert opinion on …, 2020 - Taylor & Francis
… been applied to correct the dysregulated miRNA in cancer cells. The authors also …
miRNA-based therapeutic agents. Expert opinion: Application of miRNA-based therapeutics for …

microRNAs as novel therapeutics in cancer

G Romano, M Acunzo, P Nana-Sinkam - Cancers, 2021 - mdpi.com
… There is a dedicated focus on the different methods available for microRNA deliverydelivery
methods. Finally, we discuss the ongoing clinical trials that are using microRNAs for cancer

Nanoparticle-based delivery of tumor suppressor microRNA for cancer therapy

CP O'Neill, RM Dwyer - Cells, 2020 - mdpi.com
… MiR-34a encapsulated in a liposomal formulation, coined MRX34, was tested as a viable TS
miRNA delivery therapy in a preclinical liver cancer study. After IV injection of MRX34 in two …

Exosome based miRNA delivery strategy for disease treatment

Z Fang, X Zhang, H Huang, J Wu - Chinese Chemical Letters, 2022 - Elsevier
… is mainly used in cancer treatment, nerve regeneration, … medicine, so this chapter mainly
introduces the research progress of exosomes as miRNA vectors when treating cancer, …