… of mitochondrial DNA transcription. In this review, we will discuss recent advances in the
structure and mechanism of mitochondrial transcription … control mitochondrial DNA transcription, …

… as mitochondrial DNA (mtDNA), which in mammalian cells contains 37 … mitochondria (1–3).
Besides these proteins, however, most (99%) of mitochondrial proteins in mammalian cells …

… Advances in cryo-electron microscopy (cryoEM) have revealed unique features and
modes of the mitochondrial transcription, translation and RNA-processing machinery in …

… Mammalian mitochondria contain multiple copies of a circular, double-stranded DNA … In
this review, we discuss our current understanding of mtDNA replication in mammalian cells and …

… Here we describe first-in-class specific inhibitors of mitochondrial transcription (IMTs) that
target the human mitochondrial RNA polymerase (POLRMT), which is essential for biogenesis …

… as cell signaling molecules. Aside from the import of exogenous fatty acids, mammalian cells
… diverse array of cellular fatty acids (Smith, 1994). However, it is much less appreciated that …

… roles, mitochondria as signaling organelles dictate stem cell fate … ideas on how mitochondria
control mammalian stem cell fate and … , pyruvate metabolism, and mitochondrial dynamics. …

… to silence translation in purified mitochondria. In vitro import of … mitochondrial mRNAs. By
applying this approach, we conclude that the bicistronic, overlapping ATP8/ATP6 transcript is …

… mitochondrial respiration to facilitate cellular adaptation to different metabolic and growth
conditions. In particular, we focus on transcriptional, … that promote mitochondrial respiratory …

… When mitochondrial protein import capacity is reduced … drive transcription of genes involved
in mitochondrial proteostasis … the mitochondrial network with the induction of a mitochondrial …