… Congenital hyperinsulinism (CHI) is caused by an unregulated insulin secretion by the …
neonatal period, infancy and childhood [3]. The glucose consumption by the neonatal and infant …

… The purpose of this report is to review our current knowledge of these three major forms of
neonatal hyperinsulinism as a foundation for the diagnosis and management of hypoglycemia …

… hyperinsulinemia and CH, this article presents a review on the literature of hyperinsulinism
in neonates … by which mechanisms CH might develop during hyperinsulinemic states and in …

… During the neonatal and infant period, hyperinsulinemic hypoglycemia (HH) is the most …
Following a better knowledge of the pathophysiology and the molecular mechanisms of disease, …

… hyperinsulinemic hypoglycemia of infancy or PHHI, as it is now understood that the disease
can be neonatal, … With better understanding of the molecular mechanism underlying insulin …

… The animal model used in this study does not fully mimic IDM due to the lack of hyperinsulinism.
It is unclear how this pathway works in humans, and additional research would improve …

… for the majority of them the molecular mechanism leading to … hyperinsulinism” OR “neonatal
hyperinsulinism” OR (hypoglycemia AND insulin) OR hyperinsulinemia OR hyperinsulinemic …

… Because of its high rate of glucose consumption, the neonatal brain is more prone to
hypoglycemic brain injury. In addition, hyperinsulinism decreases ketone production, which serves …

… Neonates with symptomatic hyperinsulinemic hypoglycemia generate inappropriately
low serum cortisol counterregulatory hormonal responses. J Clin Endocrinol Metab. 2003;88(9):…

… 48–72 hours without a clear cause (eg prematurity, growth restriction, small or large for
gestational age) in a full-term infant, there is reason to suspect congenital hyperinsulinism (2). …