PEGylated erlotinib HCl injectable nanoformulation for improved bioavailability
H Bhargave, H Nijhawan, KS Yadav - AAPS PharmSciTech, 2023 - Springer
… An in vitro drug release study was performed in order to determine the release behavior of
the Erlotinib HCl from nanoparticles. For this study, freeze-dried nanoparticles of Erlotinib HCl …
the Erlotinib HCl from nanoparticles. For this study, freeze-dried nanoparticles of Erlotinib HCl …
Role of solid lipid nanoparticles as drug delivery vehicles on the pharmacokinetic variability of Erlotinib HCl
R Rampaka, K Ommi, N Chella - Journal of Drug Delivery Science and …, 2021 - Elsevier
… Presence of food shows the variability in pharmacokinetics of erlotinib especially in absorption.
The present study is aimed at developing solid lipid nanoparticles for Erlotinib HCl and …
The present study is aimed at developing solid lipid nanoparticles for Erlotinib HCl and …
… therapy in unresectable stage III epidermal growth factor receptor mutation-positive non-small cell lung cancer: a multicenter, randomized, open-label, phase 2 trial
L Xing, G Wu, L Wang, J Li, J Wang, Z Yuan… - International Journal of …, 2021 - Elsevier
… In the RECEL study, we investigated the efficacy and tolerability of erlotinib versus
chemotherapy (etoposide/cisplatin), both with concurrent RT, for unresectable stage III NSCLC …
chemotherapy (etoposide/cisplatin), both with concurrent RT, for unresectable stage III NSCLC …
Central composite design augmented quality-by-design-based systematic formulation of erlotinib hydrochloride-loaded chitosan-poly (lactic-co-glycolic acid) …
… Aim: This study aimed to formulate erlotinib hydrochloride (ERT-HCL)-loaded chitosan (CS)
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …
and poly (lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) using Quality-by-Design (QbD) …
Phase I/II study of erlotinib plus S-1 for patients with previously treated non-small cell lung cancer: Thoracic Oncology Research Group (TORG) 0808/0913
Y Nakahara, T Shimokawa, Y Misumi, N Nogami… - Investigational New …, 2021 - Springer
… study was that it was a clinical trial with small sample size. Also, since many trials showed that
the efficacy of erlotinib … III studies, and thus the expectations for the combination therapy of …
the efficacy of erlotinib … III studies, and thus the expectations for the combination therapy of …
Injectable microspheres of erlotinib hydrochloride for sustained drug release.
TV DESHMUKH, RC DOIJAD… - … Research (09752366), 2020 - search.ebscohost.com
… The aim of this research was to formulation and evaluation of Injectable microspheres of
Erlotinib Hydrochloride. Erlotinib HCL Injectable microspheres were prepared by O/W emulsion …
Erlotinib Hydrochloride. Erlotinib HCL Injectable microspheres were prepared by O/W emulsion …
Comparing efficacy of erlotinib and bevacizumab combination with erlotinib monotherapy in patients with advanced non-small cell lung cancer (NSCLC): A systematic …
P Sakharkar, S Kurup - Diseases, 2023 - mdpi.com
… Nine studies comprising 1698 patients with NSCLC were included in this meta-analysis, of
whom 850 were treated with erlotinib plus bevacizumab, and 848 with erlotinib. The erlotinib …
whom 850 were treated with erlotinib plus bevacizumab, and 848 with erlotinib. The erlotinib …
Stability and formulation of erlotinib in skin creams
D Nguyen, PH Secrétan, C Cotteret… - Molecules, 2022 - mdpi.com
… of hydrochloric acid (HCl), sodium hydroxide (NaOH), and hydrogen peroxide (H 2 O 2 ) [12,13],
the impact of formulation change needs to be assessed. As a result, this study was …
the impact of formulation change needs to be assessed. As a result, this study was …
A randomized phase II trial of bevacizumab vs. bevacizumab and erlotinib as first-line consolidation after carboplatin, paclitaxel, and bevacizumab in newly diagnosed …
S Campos, U Matulonis, S Berlin, N Horowitz… - International Journal of …, 2022 - Springer
… We conducted a randomized exploratory phase II multicenter trial that evaluated the
efficacy and tolerability of bevacizumab (A) and bevacizumab/erlotinib (AE) as first-line …
efficacy and tolerability of bevacizumab (A) and bevacizumab/erlotinib (AE) as first-line …
Efficacy and safety of erlotinib combined with bevacizumab in the treatment of non-small cell lung cancer: a systematic review and meta-analysis
K Zhou, S Zhao, W Guo, L Ding - Medicine, 2020 - journals.lww.com
… Moreover, little research is available on adverse events associated with combining erlotinib
and bevacizumab. To resolve these issues, we conducted a meta-analysis and systematic …
and bevacizumab. To resolve these issues, we conducted a meta-analysis and systematic …
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