The inflammasome NLR family pyrin domain-containing protein 3 (NLRP3) as a novel therapeutic target for idiopathic pulmonary fibrosis
RMLC Biancatelli, PA Solopov, JD Catravas - The American Journal of …, 2022 - Elsevier
… of NLRP3 inflammasome activation. 3,4-Methylenedioxy-β-nitrostyrene does not affect …
The rosemary and sage polyphenol, carnosol, inhibits NLRP3 inflammasome activation by …
The rosemary and sage polyphenol, carnosol, inhibits NLRP3 inflammasome activation by …
Target of MCC950 in inhibition of NLRP3 inflammasome activation: a literature review
D Wu, Y Chen, Y Sun, Q Gao, H Li, Z Yang, Y Wang… - Inflammation, 2020 - Springer
… inflammasome (not shown). However, it is signaled by TLR4-caspase-8 that works upstream
of NLRP3 … and alternative inflammasome pathways, NLRP3 inflammasome activation leads …
of NLRP3 … and alternative inflammasome pathways, NLRP3 inflammasome activation leads …
Therapeutic regulation of the NLRP3 inflammasome in chronic inflammatory diseases
… therapeutic applications targeting the NLRP3 inflammasome to … This review extensively
discusses NLRP3 inflammasome-… may be a promising prognostic factor and therapeutic target. …
discusses NLRP3 inflammasome-… may be a promising prognostic factor and therapeutic target. …
Inhibition of NLRP3 inflammasome: a prospective target for the treatment of ischemic stroke
YS Feng, ZX Tan, MM Wang, Y Xing, F Dong… - Frontiers in Cellular …, 2020 - frontiersin.org
… Thus, NLRP3 inflammasome is an ideal therapeutic target … of NLRP3 inflammasome, the
role of NLRP3 inflammasome in … , and several treatments targeting NLRP3 inflammasome in …
role of NLRP3 inflammasome in … , and several treatments targeting NLRP3 inflammasome in …
[HTML][HTML] The involvement of NLRP3 inflammasome in the treatment of neurodegenerative diseases
YS Feng, ZX Tan, LY Wu, F Dong, F Zhang - Biomedicine & …, 2021 - Elsevier
… This research will help locate precise drug targets and develop better therapeutic methods.
Currently, studies on the role of NLRP3 inflammasome in neurodegenerative disease are still …
Currently, studies on the role of NLRP3 inflammasome in neurodegenerative disease are still …
NLRP3 inflammasome and inflammatory diseases
Z Wang, S Zhang, Y Xiao, W Zhang… - Oxidative medicine …, 2020 - Wiley Online Library
… NLRP3 inflammasome activation. Several factors including NO [51] and Ca 2+ [52] can lead
to MtD, which may also trigger the NLRP3 inflammasome activation … the NLRP3 secondary …
to MtD, which may also trigger the NLRP3 inflammasome activation … the NLRP3 secondary …
The NLRP3 inflammasome in burns: a novel potential therapeutic target
H Li, J Zhao, L Cao, Q Luo, C Zhang, L Zhang - Burns & Trauma, 2024 - academic.oup.com
… help find optimal therapeutic targets to promote … NLRP3 inflammasome in burn wound
healing, as well as the preclinical studies of the involvement of NLRP3 inhibitors in burn treatment…
healing, as well as the preclinical studies of the involvement of NLRP3 inhibitors in burn treatment…
Strategies for targeting the NLRP3 inflammasome in the clinical and preclinical space
AG Schwaid, KB Spencer - Journal of Medicinal Chemistry, 2020 - ACS Publications
… The NLRP3 inflammasome is a promising drug target. The breadth of indications it is implicated
in speak to the apparent centrality of this pathway. In the next several years, as the most …
in speak to the apparent centrality of this pathway. In the next several years, as the most …
[HTML][HTML] Targeting the NLRP3 inflammasome as new therapeutic avenue for inflammatory bowel disease
QL Chen, HR Yin, QY He, Y Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… a promising drug target for the treatment of … of NLRP3 expression and inflammasome
activation, with emphasis on the available small molecule inhibitors targeting NLRP3 inflammasome…
activation, with emphasis on the available small molecule inhibitors targeting NLRP3 inflammasome…
The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases
… of Cl − efflux in NLRP3 inflammasome assembly (Compan et … role in NLRP3 inflammasome
activation in conjunction with K … by ionophores cannot activate the NLRP3 inflammasome, …
activation in conjunction with K … by ionophores cannot activate the NLRP3 inflammasome, …