… events and suggested that NLRP3 inflammasome is a key driver of … the role of NLRP3
inflammasome in vascular diseases, in … discuss NLRP3 inflammasome as a therapeutic target for …

… also focus on the therapeutic implications of targeting novel inhibitors of the NLRP3
inflammasome or of novel … These microRNAs might therefore be effective therapeutic targets for …

… Table 1 shows a list of agents in various stages of development that target the NLRP3
inflammasome. Therapeutics targeting IL-1β and the NLRP3 inflammasome pathway have …

… Upon cleavage by caspase-11, the amino fragment of GSDMD-N initiates pyroptosis and
is also associated with NLRP3 inflammasome activation, leading to upregulation of IL-1β [21]. …

… in the activation and inactivation of NLRP3 inflammasome. This … basis of NLRP3 inflammasome
activation and inactivation. … of new therapies directed at NLRP3 inflammasome related …

… We conclude that NLRP3 inflammasome activation with enhanced IL-1 activity during
AMI contributes to the risk of HF and that IL-1 targeting therapy may prevent recurrent …

… NLRP3 inflammasome has become a promising drug target … identified to target the NLRP3
inflammasome pathway directly or … development targeting the NLRP3 inflammasome pathway. …

… the NLRP3 inflammasome may be an effective therapeutic target for … regarding the activation
of the NLRP3 inflammasome and its … that target the suppression of NLRP3 inflammasome. …

… therapeutic targets and … NLRP3 inflammasome on the regulation of immune cells, antitumor
immunity and efficiency of immunotherapy. In summary, targeting the NLRP3 inflammasome …

… Recent studies have revealed that NLRP3 inflammasome activation … NLRP3 inflammasome
activation, suggesting that cell death is closely related to NLRP3 inflammasome activation. In …