Dengue vaccines: ongoing challenges and current status in the advancement of different candidates

M Hassan, A Hassan, M Farooq, S Afzal… - Critical Reviews™ in …, 2021 - dl.begellhouse.com
… has been an ambitious task due to the presence of four different dengue serotypes … the
ongoing challenges in the construction of a dengue vaccine and the current status of the vaccine

[HTML][HTML] Dengue vaccines: an update

JM Torres-Flores, A Reyes-Sandoval, MI Salazar - BioDrugs, 2022 - Springer
… Finally, we emphasize the safety-related challenges associated with the risk of vaccine-…
However, a phase III trial is still ongoing and the final conclusions on efficacy, side or rare …

An update on dengue vaccine development, challenges, and future perspectives

F Idris, DHR Ting, S Alonso - Expert Opinion on Drug Discovery, 2021 - Taylor & Francis
… of dengue vaccination, and discusses the challenges that … Finally, an ongoing clinical trial
led by WRAIR is addressing … two dengue vaccine candidates, namely the inactivated vaccine

Challenges on the development of a dengue vaccine: a comprehensive review of the state of the art

J Pintado Silva… - Journal of General …, 2023 - microbiologyresearch.org
… severe dengue in young, vaccinated recipients. … a dengue vaccine. In this review we have
conducted a detailed overview of the DENV vaccine landscape, focusing on nine vaccines in …

[HTML][HTML] Challenges in dengue vaccines development: pre-existing infections and cross-reactivity

AM Izmirly, SO Alturki, SO Alturki, J Connors… - Frontiers in …, 2020 - frontiersin.org
… TV003/TV005 (NCT01506570) and TDV/DENVax/TAK003 (NCT02302066) are two promising
live-attenuated vaccine candidates currently ongoing in phase 3 clinical trials (39, 40). …

[PDF][PDF] Dengue vaccine: Global development update

E Prompetchara, C Ketloy, SJ Thomas… - Asian Pac J Allergy …, 2020 - researchgate.net
… are ongoing to find a better effective and accessible dengue … With all those challenges, it is
interesting to see all research … effective and accessible dengue vaccine for people needed is …

[HTML][HTML] Facing the escalating burden of dengue: Challenges and perspectives

GN Malavige, P Sjö, K Singh… - PLOS Global Public …, 2023 - journals.plos.org
… in dengue vaccines will hopefully reduce the burden of dengue… With the ongoing threat of
COVID-19, influenza and other … face the challenge of treating patients with dengue, COVID-19, …

Challenges Associated with Dengue Vaccine Development

S Jeyapalan, VN Fernando, NK Jahan… - … Research Journal of …, 2021 - research.monash.edu
vaccine research challenging. Dengvaxia, a dengue vaccine for seropositive individuals
between the ages of 9-45 has been licensed despite the significant challenges. Several other …

[HTML][HTML] Dengue vaccines: Current status and future perspectives

V Kamath, AB Aishwarya - APIK Journal of Internal Medicine, 2024 - journals.lww.com
… However, challenges remain in developing a dengue vaccine. This includes considering …
Advances in vaccine technology, ongoing clinical trials, and the search for new platforms …

[HTML][HTML] Antibody-dependent enhancement: a challenge for developing a safe dengue vaccine

R Shukla, V Ramasamy, RK Shanmugam… - Frontiers in cellular …, 2020 - frontiersin.org
… The challenges associated with whole DENV-based vaccine strategies necessitate re-focusing
our attention toward the designed dengue vaccine … If the designed vaccines elicited …