miRNA profile in ovarian cancer

S Ghafouri-Fard, H Shoorei, M Taheri - Experimental and molecular …, 2020 - Elsevier
miRNAs can modulate expression of several ovarian cancer-… as a tumor suppressor miRNA
which directly targets CDK4 … – 5-aza-CdR treatment could increase miR-145 expression. miR…

The role of miRNA in ovarian cancer: an overview

L Zhao, X Liang, L Wang, X Zhang - Reproductive sciences, 2022 - Springer
… of an effective target for early screening, treatment, and prognostic prediction of epithelial
ovarian cancer is necessary for researches in this field. MicroRNAs (miRNAs) are a class of …

The clinical impact of intra‐and extracellular miRNAs in ovarian cancer

K Yoshida, A Yokoi, T Kato, T Ochiya… - Cancer …, 2020 - Wiley Online Library
… Hence, downregulation of these miRNAs targeting DNA repair-related genes is … targets of
miRNAs are involved in treatment resistance, miRNAs can act as potential therapeutic targets

Ovarian cancer: biomarkers and targeted therapy

MR Radu, A Prădatu, F Duică, R Micu, SM Creţoiu… - Biomedicines, 2021 - mdpi.com
… in ovarian cancers), pathological features, treatment response and prognosis of different …
miRNAs are valuable biomarkers in ovarian malignancy detection. Some members from the …

The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance–a focus on signaling pathways interplay

A Ismail, AI Abulsoud, D Fathi, A Elshafei… - … -Research and Practice, 2022 - Elsevier
… or tumor suppressors via degrading or impeding target mRNA … signaling pathways, miRNAs
promote carcinogenesis and … OC treatment, its 1ry goal is to maximize tumor management

Role of microRNAs as clinical cancer biomarkers for ovarian cancer: a short overview

CE Staicu, DV Predescu, CM Rusu, BM Radu… - Cells, 2020 - mdpi.com
… may be affected by pharmacological treatments and, therefore, we can assume that they
have the potential to serve as therapeutic targets/agents for the treatment of ovarian cancer. …

Advances in ovarian cancer treatment beyond PARP inhibitors

F Aliyuda, M Moschetta, A Ghose… - … Cancer Drug Targets, 2023 - ingentaconnect.com
MicroRNAs have also become novel biomarkers for the therapy and clinical … the targeting
of growth-dependent pathways in ovarian cancer and assesses current data related to targeted

Hsa_circ_0009910: oncogenic circular RNA targets microRNA-145 in ovarian cancer cells

Y Li, S Lin, N An - Cell cycle, 2020 - Taylor & Francis
… In our study, we predicted miRNAs targets of hsa_circ_0009910 using the bioinformatics …
be applied for the treatment of ovarian cancer. However, further clinical confirmation is required. …

MicroRNAs as the critical regulators of Cisplatin resistance in ovarian cancer cells

M Moghbeli - Journal of ovarian research, 2021 - Springer
miRNAs based on their targets to clarify their probable molecular mechanisms during cisplatin
resistance in ovarian tumor … OC cells to DDP-treatment via mTOR targeting [55]. The mTOR…

The role of microRNAs in epithelial ovarian cancer metastasis

VHL Nguyen, C Yue, KY Du, M Salem… - International journal of …, 2020 - mdpi.com
Ovarian cancer is the fifth leading cause of cancer-related deaths in females [1]. Based on the
cell origin where ovarian tumors arise, ovarian cancer is … targets for cancer treatment [314]. …