[HTML][HTML] Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors

D Szukiewicz, S Trojanowski, A Kociszewska… - International journal of …, 2022 - mdpi.com
ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive
age. Despite its incidence, the syndrome … , endocrine, and behavioral factors. Primary clinical …

Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
… Besides summarizing the genetic factors linked to PCOS, we highlight epigenetic
modulation as a mechanism that bridges early-life exposures and subsequent phenotypes in …

Polycystic ovary syndrome: the epigenetics behind the disease

MC Eiras, DP Pinheiro, KAM Romcy, RA Ferriani… - Reproductive …, 2022 - Springer
… etiology of this syndrome [11]. This suggests a complex and multifactorial origin of PCOS,
in which genetic alterations, environmental factors, and epigenetic modifications contribute to …

The role of genetics, epigenetics and lifestyle in polycystic ovary syndrome development: the state of the art

V Bruni, A Capozzi, S Lello - Reproductive Sciences, 2022 - Springer
… of major genetic, epigenetic and environmental factors on the appearance of this … epigenetics
in the appearance of PCOS. Several genes, including those related to adrenal and ovarian

[HTML][HTML] Characterization of DNA methylation and screening of epigenetic markers in polycystic ovary syndrome

P Cao, W Yang, P Wang, X Li… - Frontiers in cell and …, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a … ovary. Although the etiology of PCOS is largely
unknown, many studies suggest that aberrant DNA methylation is an important contributing factor

[HTML][HTML] Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process

NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura… - Cell metabolism, 2021 - cell.com
… Environmental factors exert their effects via the induction of epigenetic changes such as DNA
… However, there are very few studies focusing on the epigenetic changes associated with …

[HTML][HTML] DNA methylation in polycystic ovary syndrome: emerging evidence and challenges

YN Liu, Y Qin, B Wu, H Peng, M Li, H Luo… - Reproductive Toxicology, 2022 - Elsevier
epigenetic factors play an important role in PCOS. DNA methylation is the most widely studied
epigenetic … At present, changes of DNA methylation have been found in serum, ovarian, …

Metformin improves epigenetic modification involved in oocyte growth and embryo development in polycystic ovary syndrome mice model

S Amani Abkenari, L Safdarian, F Amidi… - Molecular …, 2021 - Wiley Online Library
… can be regulated by several maternal and zygote epigenetics factors (Rivera, 2010). …
polycystic ovary syndrome (PCOS) with excess androgen may be associated to epigenetic

[HTML][HTML] Identification of epigenetic interactions between microRNA and DNA methylation associated with polycystic ovarian syndrome

Z Mao, T Li, H Zhao, Y Qin, X Wang… - Journal of Human …, 2021 - nature.com
… is a causal factor for polycystic ovarian syndrome. However, the epigenetic interactions …
domain sequencing on ovarian granulosa cells to reveal the epigenetic interactions involved in …

Polycystic ovary syndrome

AE Joham, RJ Norman, E Stener-Victorin… - The lancet Diabetes & …, 2022 - thelancet.com
… The cause is complex, and includes genetic and epigenetic susceptibility, hypothalamic
and ovarian dysfunction, excess androgen exposure, insulin resistance, and adiposity-related …