MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a …

S Brandner, A McAleenan, C Kelly, F Spiga… - Neuro …, 2021 - academic.oup.com
… However, MGMT methylation status does not always … MGMT promoter methylation improves
response to alkylating therapy is still unknown. MGMT promoter methylation status testing is …

MGMT Promoter Methylation Predicts Overall Survival after Chemotherapy for 1p/19q-Codeleted Gliomas

CJ Kinslow, AI Rae, K Taparra, P Kumar… - Clinical Cancer …, 2023 - AACR
… , our study highlights an opportunity to increase MGMT testing nationwide for oligodendroglial
tumors. However, widespread adoption will likely not be realized until further guidance is …

Prognostic value of test (s) for O6‐methylguanine–DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma …

A McAleenan, C Kelly, F Spiga… - Cochrane Database …, 2021 - cochranelibrary.com
… In this Cochrane Review, we aimed to assess which way of measuring methylation of the
MGMT promoter best predicts survival for people with glioblastoma who are treated with …

Correlation of the quantitative level of MGMT promoter methylation and overall survival in primary diagnosed glioblastomas using the quantitative MethyQESD method

C von Rosenstiel, B Wiestler, B Haller… - Journal of clinical …, 2020 - jcp.bmj.com
… focuses on comparing MGMT promoter methylation status of various patients with their survival
time of … Associations of clinical data and MGMT promoter status were tested by χ 2 tests. …

The interaction between TERT promoter mutation and MGMT promoter methylation on overall survival of glioma patients: a meta-analysis

HG Vuong, TQ Nguyen, TNM Ngo, HC Nguyen… - BMC cancer, 2020 - Springer
MGMT promoter methylation and TERT promoter mutation on glioma patients’ overall survival
(… As a result, it is crucial to test for TERT promoter mutation and MGMT methylation in GBM …

[HTML][HTML] Predictive value of MGMT promoter methylation on the survival of TMZ treated IDH-mutant glioblastoma

R Chai, G Li, Y Liu, K Zhang, Z Zhao, F Wu… - Cancer Biology & …, 2021 - ncbi.nlm.nih.gov
… Then, we compared the PFS and overall survival (OS) of patients in different methylation
groups of … We additionally compared the predictive cutoff levels of MGMT promoter PSQ testing

Extent of MGMT promoter methylation modifies the effect of temozolomide on overall survival in patients with glioblastoma: a regional cohort study

MTC Poon, S Keni, V Vimalan, C Ip… - Neuro-Oncology …, 2021 - academic.oup.com
MGMT methylation and overall survival and evaluated the interaction between MGMT
methylation … We did not report P-values in descriptive tables to avoid multiple testing. We used the …

Prognostic and predictive impact of MGMT promoter methylation in grade 3 gliomas

W Haque, E Thong, S Andrabi, V Verma… - Journal of Clinical …, 2021 - Elsevier
… of MGMT promoter methylation in patients with grade 3 gliomas is less clear. The purpose of
the present study was to evaluate the utilization of MGMT testing … improved overall survival

Prospective Evaluation of MGMT-Promoter Methylation Status and Correlations with Outcomes to Temozolomide-Based Chemotherapy in Well-Differentiated …

N Brighi, G Lamberti, E Andrini, C Mosconi, L Manuzzi… - Current …, 2023 - mdpi.com
… were tested for MGMT-promoter methylation status before … the role of MGMT-promoter
methylation status in predicting the … was progression-free survival (PFS) by MGMT-promoter

Identifying the optimal cutoff point for MGMT promoter methylation status in glioblastoma

N Nguyen, J Redfield, M Ballo, M Michael… - CNS …, 2021 - Taylor & Francis
… poor prognosis and overall survival (OS), commonly less than two years with a 5.6% 5-year …
cutoff value for determining MGMT promoter methylation status by PSQ testing will allow for …