The non‐enzymatic oxidation of phosphatidylethanolamine and phosphatidylserine and their intriguing roles in inflammation dynamics and diseases
M Santos, T Melo, T Maurício, H Ferreira, P Domingues… - FEBS letters - Wiley Online Library
… Their oxidized forms, OxPE and OxPS, play significant roles in inflammation and immune …
(LPS), suggesting a protective role against exacerbated immune responses, similar to OxPC. …
(LPS), suggesting a protective role against exacerbated immune responses, similar to OxPC. …
A comparative study about the neuroprotective effects of DHA-enriched phosphatidylserine and EPA-enriched phosphatidylserine against oxidative damage in …
YW Wang, Q Li, XY Li, YC Zhao, CC Wang, CH Xue… - Marine drugs, 2023 - mdpi.com
… protein 2 as a neuron-specific marker for the detection of primary cultured neurons [18]. … be
oxidized thus playing a role in reducing oxidative damage to cells. The cellular protection may …
oxidized thus playing a role in reducing oxidative damage to cells. The cellular protection may …
[HTML][HTML] Phosphatidylserine improves aging sepsis survival, modulates gut microbiome, and prevents sepsis-associated encephalopathy
K Xu, Q Huang, Y Lyu, S Wang, Y Lu, G Qian - Biomedicine & …, 2024 - Elsevier
… We investigated the neuron death marker cleaved Caspase 3 to determine whether PS
could protect brain neurons during sepsis. Immunofluorescence staining of cortexes revealed …
could protect brain neurons during sepsis. Immunofluorescence staining of cortexes revealed …
Low concentrations of oxidized phospholipids increase stress tolerance of endothelial cells
C Mauerhofer, T Afonyushkin, OV Oskolkova… - Antioxidants, 2022 - mdpi.com
… protective action of OxPLs/Lyso-PLs. We hypothesize that … These lipids have been studied
as both markers and drivers of … , phosphatidylserine, as well as phosphatidic acid upon …
as both markers and drivers of … , phosphatidylserine, as well as phosphatidic acid upon …
Biological function and immunotherapy utilizing phosphatidylserine-based nanoparticles
FY Glassman, R Dingman, HC Yau… - Immunological …, 2020 - Taylor & Francis
… The oxidation of fatty acid acyl chains on PS triggers specific signals, marking the cells to …
PS blocking strategies have been investigated for host protection from viral entry and infection. …
PS blocking strategies have been investigated for host protection from viral entry and infection. …
Proteomic and lipidomic analyses reveal saturated fatty acids, phosphatidylinositol, phosphatidylserine, and associated proteins contributing to intramuscular fat …
J Zhou, Y Zhang, J Wu, M Qiao, Z Xu, X Peng… - Journal of Proteomics, 2021 - Elsevier
… PLIN1, the most abundant adipocyte-specific protein, coats lipid droplets to protect them …
the suppression of fatty acid β-oxidation [72]. ADIPOQ is a marker for mature adipocytes, and its …
the suppression of fatty acid β-oxidation [72]. ADIPOQ is a marker for mature adipocytes, and its …
The role of oxidized phospholipids in the development of disease
J Nie, J Yang, Y Wei, X Wei - Molecular aspects of medicine, 2020 - Elsevier
… Oxidized phospholipids (OxPLs), complex mixtures of phospholipid oxidation products
generated during normal or pathological processes, are increasingly recognized to show …
generated during normal or pathological processes, are increasingly recognized to show …
Oxidized phospholipids as novel mediators of neurodegeneration
… Inflammation and oxidative stress occurring in the CNS promote lipid peroxidation,
leading to the generation of oxidized phospholipids such as oxidized phosphatidylcholines (OxPCs). …
leading to the generation of oxidized phospholipids such as oxidized phosphatidylcholines (OxPCs). …
Oxidized phospholipids in healthy and diseased lung endothelium
P Karki, KG Birukov - Cells, 2020 - mdpi.com
… -protective and deleterious aspects of oxidized phospholipids and discuss their therapeutic
potential including engineering of stable analogs of oxidized … as in vivo markers of oxidative …
potential including engineering of stable analogs of oxidized … as in vivo markers of oxidative …
Preparation, characterization, evaluation of neuroprotective effect, and related mechanisms of phosphatidylserine emulsion in 5-and 12-week old mice
B Liu, N Zhang, J Yang, W Sun, R Zhang… - Journal of Agricultural …, 2022 - ACS Publications
… Here, we provide evidence about a neuro-protective effect of PS emulsion on learning
and memory capacity and myelination in 5- and 12-week old mice via stimulating the BDNF/TrkB/…
and memory capacity and myelination in 5- and 12-week old mice via stimulating the BDNF/TrkB/…