… have provided strong evidence on the role of PI3K/AKT/mTOR pathway in PDAC, clinical …
PI3K/AKT/mTOR pathway could provide valuable assets for treatment of pancreatic cancer …

… pancreatic cancer patients. In this review, we focus on PI3K/AKT/mTOR inhibitors that have
shown great anti-tumor potential in studies performed on xenograft models and pancreatic …

… , and could activate PI3K/Akt pathway by interacting with the SH3 domain of PI3K regulatory
… PAK4 and PI3K/Akt pathway. Western blot analysis showed that the levels of PAK4, p-Akt, p-…

… fisetin obviously dampens pancreatic cancer progress in vitro … repressed pancreatic cancer
via explicitly targeting PI3K/AKT/… a prospective anti-cancer drug for pancreatic cancer, as well …

… We demonstrated for the first time that Rhein can inhibit the PI3K/AKT pathway and display
a … the PI3K/AKT pathway in various tumor cells treated with natural anti-tumor drugs 46 , 47 . …

… Carboxypeptidase A4 (CPA4), as a novel tumor biomarker, is prevalently observed in various
cancers. However, the potential role of CPA4 in pancreatic cancer (PC), to our knowledge, …

… of PI3K/AKT/GSK signalling. The present study demonstrated NGF/TrkA promoted the PC
cell proliferation and invasion in the co-culture system by the activation of the PI3K/AKT/GSK …

… the proliferation, apoptosis and autophagy of human pancreatic cancer (PC) cell lines in vitro
… to establish an orthotopic pancreatic tumor model in nude mice. Tumor‑bearing nude mice …

… the levels of p-AKT, AKT, p-PI3K and PI3K in pancreatic cancer cells. As displayed in …
AKT/AKT and p-PI3K/PI3K were both reduced than that in si-NC group in the two pancreatic cancer …

… MiR-139-5p could regulate and affect the protein expression of P13K and Akt associated …
suppress PANC tumor growth and the expressions of SLC7A11, p-PI3K, p-Akt in tumor tissues. …