Risk and Prognostic Factors for BRAFV600E Mutations in Papillary Thyroid Carcinoma

X Wei, X Wang, J Xiong, C Li, Y Liao… - BioMed Research …, 2022 - Wiley Online Library
… We aim to investigate the risk factors that may predict the BRAF V600E mutation potential
of … A total of 9,908 papillary thyroid carcinoma patients with average 74.6% BRAF V600E …

[HTML][HTML] The Impact of BRAF mutation on the recurrence of papillary thyroid carcinoma: A meta-analysis

X Li, H Kwon - Cancers, 2020 - mdpi.com
BRAF V600E mutation was associated with an increased recurrence rate of papillary thyroid
carcinoma … -analysis to assess the impact of the BRAF V600E mutation on PTC recurrences. …

[HTML][HTML] The prognostic significance of BRAF gene analysis in children and adolescents with papillary thyroid carcinoma: a systematic review and meta-analysis

EP Kotanidou, S Giza, VR Tsinopoulou, K Margaritis… - Diagnostics, 2023 - mdpi.com
… of extra-thyroid disease, we did not demonstrate any association of BRAF gene mutation …
High quality data on the effect of BRAF gene mutation on vascular invasion is lacking in the …

… of Molecular Methods and BRAF Immunohistochemistry (VE1 Clone) for the Detection of BRAF V600E Mutation in Papillary Thyroid Carcinoma: A Meta-Analysis

KG Parker, MG White, NA Cipriani - Head and neck pathology, 2020 - Springer
… of the thyroid gland is papillary thyroid carcinoma (PTC). The … %) is a missense mutation
in the BRAF oncogene, valine (V) … of the MAPK pathway, either BRAF-like and RAS-like [5]. …

BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer

Y Tao, F Wang, X Shen, G Zhu, R Liu… - The Journal of …, 2021 - academic.oup.com
BRAF V600E, through overactivating the … that BRAF V600E might play an important role in
LNM-related mortality risk in PTC, thus differentiating LNM in wild-type BRAF PTC and BRAF-…

Characterization of Subtypes of BRAF-Mutant Papillary Thyroid Cancer Defined by Their Thyroid Differentiation Score

L Boucai, V Seshan, M Williams… - The Journal of …, 2022 - academic.oup.com
BRAF-mutant PTCs from the TCGA Thyroid Cancer (THCA) study (15). We defined 2 subgroups
of BRAF … relatively preserved expression of thyroid differentiation genes (BRAF-TDS hi ; …

[HTML][HTML] The BRAF V600E mutation is a predictor of the effect of radioiodine therapy in papillary thyroid cancer

J Ge, J Wang, H Wang, X Jiang, Q Liao, Q Gong… - … of Cancer, 2020 - ncbi.nlm.nih.gov
Thyroid cancer primarily includes the following four pathological … : papillary thyroid carcinoma,
follicular thyroid carcinoma, undifferentiated carcinoma and medullary thyroid carcinoma. …

[HTML][HTML] Targeting myeloid derived suppressor cells reverts immune suppression and sensitizes BRAF-mutant papillary thyroid cancer to MAPK inhibitors

P Zhang, H Guan, S Yuan, H Cheng, J Zheng… - Nature …, 2022 - nature.com
… Understanding how BRAF pathway stimulates … that BRAF V600E promotes thyroid cancer
development by increasing myeloid-derived suppressor cells (MDSCs) penetrance. This BRAF

Genetic trio of BRAF and TERT alterations and rs2853669TT in papillary thyroid cancer aggressiveness

R Liu, G Zhu, J Tan, X Shen… - … of the National Cancer …, 2024 - academic.oup.com
… Background: BRAF V600E and TERT promoter alterations … for precision management of
papillary thyroid cancer. It remains … genomic DNA from papillary thyroid cancer in 608 patients (…

[HTML][HTML] Papillary thyroid cancer organoids harboring BRAFV600E mutation reveal potentially beneficial effects of BRAF inhibitor-based combination therapies

D Chen, X Su, L Zhu, H Jia, B Han, H Chen… - Journal of Translational …, 2023 - Springer
Papillary thyroid cancer organoids harboring BRAF V600E mutation reveal potentially
beneficial effects of BRAFPapillary thyroid cancer (PTC), which is often driven by acquired …