Adverse outcome pathway of fine particulate matter leading to increased cardiovascular morbidity and mortality: an integrated perspective from toxicology and …

Y Yu, Q Sun, T Li, X Ren, L Lin, M Sun, J Duan… - Journal of hazardous …, 2022 - Elsevier
Fine particulate matter (PM 2.5 ) exposure is a major threat to public health, and is listed as
one of the leading factors associated with global premature mortality. Among the adverse …

Fifteen Years of Airborne Particulates in Vitro Toxicology in Milano: Lessons and Perspectives Learned

EM Longhin, P Mantecca, M Gualtieri - International Journal of Molecular …, 2020 - mdpi.com
… , including particulate matter (PM) chemical and microbiological characterization, in vitro
and in vivo toxicological effects, as well as clinical and epidemiological studies [5,6,7,8]. …

Particulate matter-induced cardiovascular dysfunction: a mechanistic insight

NU Ain, SUR Qamar - Cardiovascular Toxicology, 2021 - Springer
… The main constituent of highly polluted air is particulate matter (PM) which creates haze and
decreases the air quality. PM is a complex mixture of organic compounds, aerosols, gases, …

A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence

T Li, Y Yu, Z Sun, J Duan - Particle and fibre toxicology, 2022 - Springer
… Previous reviews have preliminary illustrated relevant mechanisms from the perspective of
PM-related cell death patterns or the perspective of certain diseases or systems, pointing out …

Particulate matter (PM) oxidative potential: Measurement methods and links to PM physicochemical characteristics and health effects

L He, J Zhang - Critical Reviews in Environmental Science and …, 2023 - Taylor & Francis
… pathophysiologic pathway linking particulate matter (PM) … Within the context of toxicology,
PM oxidative potential (OP) … , and the epidemiological and toxicological evidence on whether …

Ambient fine particulate matter and cancer: Current evidence and future perspectives

H Liu, X Zhang, Z Sun, Y Chen - Chemical Research in Toxicology, 2023 - ACS Publications
The high incidence of cancer has placed an enormous health and economic burden on
countries around the world. In addition to evidence of epidemiological studies, conclusive …

[HTML][HTML] On fine particulate matter and COVID-19 spread and severity: An in vitro toxicological plausible mechanism

S Marchetti, M Gualtieri, A Pozzer, J Lelieveld… - Environment …, 2023 - Elsevier
… there is a lack of toxicological evidence on the role of PM 2.5 in increasing the SARS-CoV-2
infectiousness, as suggested by some epidemiological studies. From this perspective, it is …

A review on potential approach for in silico toxicity analysis of respirable fraction of ambient particulate matter

AD Gupta, T Gupta - Environmental Monitoring and Assessment, 2023 - Springer
… Epidemiological and toxicological studies have shown the adverse effect of ambient particulate
matter (PM) on respiratory and cardiovascular systems inside the human body. Various …

[HTML][HTML] The impact of particulate matters on apoptosis in various organs: mechanistic and therapeutic perspectives

SM Aghaei-Zarch, AHS Nia, M Nouri… - Biomedicine & …, 2023 - Elsevier
… Ecological air contamination is the non-homogenous suspension of insoluble particles
into gas or/and liquid fluids known as particulate matter (PM). It has been discovered that …

Toxicity of airborne particles—established evidence, knowledge gaps and emerging areas of importance

FJ Kelly, JC Fussell - … Transactions of the Royal Society A, 2020 - royalsocietypublishing.org
… the health effects of airborne particulate matter (PM), particularly cardiorespiratory effects
of combustion-related particles. This has been matched by toxicological research to define …