Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study

CE Wu, CF Chang, CY Huang, CT Yang, CHS Kuo… - BMC cancer, 2021 - Springer
… for patients with epidermal growth factor receptor (EGFR)-mutated non-small-cell lung
cancer (NSCLC). However, data on the use of afatinib in patients with poor performance status (…

Efficacy and Prognosis of First-Line EGFR-Tyrosine Kinase Inhibitor Treatment in Older Adults Including Poor Performance Status Patients with EGFR-Mutated Non …

CY Chang, CY Chen, SC Chang, YC Lai… - Cancer Management …, 2021 - Taylor & Francis
… For example, most of the older patients and patients with poor PS included in the current
study were treated with gefitinib or erlotinib. In addition, the sample size was relatively small, …

Osimertinib in poor performance status patients with T790M-positive advanced non-small-cell lung cancer after progression of first-and second-generation EGFR-TKI …

Y Tsubata, K Watanabe, R Saito, A Nakamura… - International Journal of …, 2022 - Springer
… in patients with poor performance status (PS) are unknown. … the performance status of each
patient during treatment. Each line shows the change in performance status (PS) of a patient

Development and validation of a prediction model of poor performance status and severe symptoms over time in cancer patients (PROVIEW+)

H Seow, P Tanuseputro, L Barbera… - Palliative …, 2021 - journals.sagepub.com
patient-reported outcomes to predict survival across the disease trajectory for patients with …
In this study, we validated the model to also predict the risk for having low performance status

Assessment of mortality and performance status in critically ill cancer patients: A retrospective cohort study

EN van der Zee, LM Noordhuis, JL Epker… - PLoS …, 2021 - journals.plos.org
performance status of critically ill cancer patients 2 … patients to mortality of patients without
cancer. Further, we aimed to identify factors associated with 2-year mortality in cancer patients. …

[HTML][HTML] Performance status in cancer: not broken, but time for an upgrade?

JM Scott, G Stene, E Edvardsen… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
… Intriguingly, despite the increasing sophistication and cost of contemporary cancer care, 5,6
evaluation of patient performance status (PS)—an integral aspect of treatment selection, …

Inter-rater reliability in performance status assessment among healthcare professionals: an updated systematic review and meta-analysis

R Chow, E Bruera, JS Temel, M Krishnan, J Im… - Supportive Care in …, 2020 - Springer
… and thereby downgrade a patient’s performance status. Coupled with … for patients with better
performance status, they may have a more optimistic bias in determining performance status

Pembrolizumab in patients with non-small-cell lung cancer of performance status 2 (PePS2): a single arm, phase 2 trial

G Middleton, K Brock, J Savage, R Mant… - The Lancet …, 2020 - thelancet.com
… have enrolled patients with performance status (PS) 0–1. However, around 18% of patients
with NSCLC are PS2, and the activity and safety of pembrolizumab in these patients is …

Modernizing clinical trial eligibility criteria: recommendations of the ASCO-Friends of Cancer Research Performance Status Work Group

A Magnuson, SS Bruinooge, H Singh, KD Wilner… - Clinical Cancer …, 2021 - AACR
Performance status (PS) is one of the most common eligibility criteria, often resulting in
exclusion of patients from trial participation and leading to clinical trial populations that are not …

Performance status assessment by using ECOG (Eastern Cooperative Oncology Group) score for cancer patients by oncology healthcare professionals

F Azam, MF Latif, A Farooq, SH Tirmazy… - Case reports in …, 2020 - karger.com
Performance status (PS) of a patient is the assessment of level of … for patients with advanced
malignancy. It is crucial to thoroughly assess and accurately document PS for each patient