[HTML][HTML] An extracellular perspective on CNS maturation: perineuronal nets and the control of plasticity

D Carulli, J Verhaagen - International Journal of Molecular Sciences, 2021 - mdpi.com
… is remarkably dynamic, changing its plasticity-associated conditions, including … perineuronal
nets contribute to the maturation of brain circuits and the regulation of adult brain plasticity

Perineuronal nets: subtle structures with large implications

H Carceller, Y Gramuntell, P Klimczak… - The …, 2023 - journals.sagepub.com
… and their potential to explain mechanisms underlying brain plasticity in health and disease.
… of perineuronal nets in the mouse brain. Representative coronal slices of mouse brain

[HTML][HTML] Transplantation of neural precursors derived from induced pluripotent cells preserve perineuronal nets and stimulate neural plasticity in ALS rats

S Forostyak, O Forostyak, JCF Kwok… - International Journal of …, 2020 - mdpi.com
… -3) and the protection of perineuronal nets around the preserved MNs. In the … plasticity by
modulating the central nervous system (CNS) extracellular matrix such as perineuronal nets

Cerebellar plasticity and associative memories are controlled by perineuronal nets

D Carulli, R Broersen, F de Winter… - Proceedings of the …, 2020 - National Acad Sciences
Perineuronal nets (PNNs) are assemblies of extracellular matrix molecules, which surround
the cell body and dendrites of many types of neuron and regulate neural plasticityplasticity

[HTML][HTML] The extracellular matrix and perineuronal nets in memory

JW Fawcett, M Fyhn, P Jendelova, JCF Kwok… - Molecular …, 2022 - nature.com
… on adult brain plasticity and perhaps learning and memory performance. It is important to
note that abolishing PNNs by enzymatic approaches may not reflect processes occurring under …

[HTML][HTML] The Role of Tenascin-C on the Structural Plasticity of Perineuronal Nets and Synaptic Expression in the Hippocampus of Male Mice

A Jakovljević, V Stamenković, J Poleksić, MIK Hamad… - Biomolecules, 2024 - mdpi.com
Neuronal plasticity is a crucial mechanism for an adapting nervous system to change. …
perineuronal nets (PNNs), the condensed forms of the extracellular matrix (ECM) around neuronal

Perineuronal Nets: From Structure to Neurological Disorders

X Li, N Li, P Zhao, D Ren, B Luo… - Current Medicinal …, 2024 - ingentaconnect.com
… molecules to regulate synaptic plasticity and neuronal activity. In this … perspective on brain
plasticity and neurological disorders. … dense matrix structures called perineuronal nets (PNN) …

The mechanisms of perineuronal net abnormalities in contributing aging and neurological diseases

Y Dong, K Zhao, X Qin, G Du, L Gao - Ageing Research Reviews, 2023 - Elsevier
… The accumulation of CSPG promotes the maturation of PNN and PV + interneurons, and
CSPG plays an important role in regulating neuron plasticity and development. In addition, the …

[HTML][HTML] Structural and functional modulation of perineuronal nets: in search of important players with highlight on tenascins

A Jakovljević, M Tucić, M Blažiková, A Korenić… - Cells, 2021 - mdpi.com
… plays a crucial role in providing optimal conditions for neuronal function. Interactions … ,
perineuronal nets (PNN), are considered a key mechanism for the regulation of brain plasticity. …

[HTML][HTML] Impact of perineuronal nets on electrophysiology of parvalbumin interneurons, principal neurons, and brain oscillations: a review

JC Wingert, BA Sorg - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
… on brain plasticity, including LTP, LTD, and paired-pulse ratio (PPR; Supplementary Table
3) followed by a discussion of how PNN removal or modifications impact brain oscillations, …