Differentiated thyroid cancer, from active surveillance to advanced therapy: toward a personalized medicine

A Matrone, MC Campopiano, A Nervo… - Frontiers in …, 2020 - frontiersin.org
thyroid cancer (DTC) showed the need of a personalized management approach.
Despite the increased diagnosis of DTC, in particular small papillary thyroid cancers, cancer-related …

Primary cell cultures for the personalized therapy in aggressive thyroid cancer of follicular origin

P Fallahi, SM Ferrari, G Elia, F Ragusa… - Seminars in Cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignancy. More than 90 % of TC is
represented by differentiated TC (DTC) arising from the follicular thyroid cells. DTC includes …

New therapies for advanced thyroid cancer

D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer … of thyroid cancer, thus allowing more personalized treatments for patients with …

[HTML][HTML] Artificial intelligence for personalized medicine in thyroid cancer: current status and future perspectives

LR Li, B Du, HQ Liu, C Chen - Frontiers in Oncology, 2021 - frontiersin.org
Thyroid cancers (TC) have increasingly been detected … step toward the goal of personalized
medicine. The diagnosis of … with several challenges regarding personalized care in TC, for …

Personalized management of differentiated thyroid cancer in real life–practical guidance from a multidisciplinary panel of experts

A Campennì, D Barbaro, M Guzzo, F Capoccetti… - Endocrine, 2020 - Springer
… Based on the clinical experience of five thyroid cancer experts, we provide a suggested
approach for assessing and diagnosing thyroid nodules in clinical practice, as well as our …

Personalized dosimetry in the context of radioiodine therapy for differentiated thyroid cancer

M Pacilio, M Conte, V Frantellizzi, MS De Feo… - Diagnostics, 2022 - mdpi.com
thyroid cancer is Differentiated Thyroid Cancer (DTC) representing more than 95% of cases
[1]. It had become the most common cancer in women by the year 2020 after breast cancer, …

Mutation based approaches to the treatment of anaplastic thyroid cancer

HC McCrary, J Aoki, Y Huang, B Chadwick… - Clinical …, 2022 - Wiley Online Library
… The treatment of anaplastic thyroid cancer (ATC) has continued to rapidly evolve over
time. Increased utilization of novel, personalized therapies based upon the tumour's somatic …

[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - … (BBA)-Reviews on Cancer, 2023 - Elsevier
… clinical practice in the future, briefly describe the resistance mechanisms of targeted therapies,
emphasizing that personalized medicine is critical to the design of second-line therapies. …

Novel inhibitor-based therapies for thyroid cancer—An update

M Ratajczak, D Gaweł, M Godlewska - International journal of molecular …, 2021 - mdpi.com
… is being developed, including personalized therapies with kinase inhibitors. Recent molecular
studies on TCs demonstrate that kinase inhibitor-based therapies might be considered as …

State of the art in the current management and future directions of targeted therapy for differentiated thyroid cancer

H Silaghi, V Lozovanu, CE Georgescu, C Pop… - International Journal of …, 2022 - mdpi.com
Two-thirds of differentiated thyroid cancer (DTC) patients with distant metastases would be
classified as radioactive iodine-refractory (RAIR-DTC), evolving into a poor outcome. Recent …