[HTML][HTML] Apolipoprotein B and cardiovascular disease: biomarker and potential therapeutic target

J Behbodikhah, S Ahmed, A Elyasi, LJ Kasselman… - Metabolites, 2021 - mdpi.com
… serum lipoprotein, is the primary therapeutic target for management and prevention of …
controversy over use of apoB as a therapeutic target in clinical practice. Ongoing coronary artery …

[HTML][HTML] CD44 as a tumor biomarker and therapeutic target

H Xu, M Niu, X Yuan, K Wu, A Liu - Experimental hematology & oncology, 2020 - Springer
… of CD44 in carcinoma potentially offering new molecular target for therapeutic intervention.
… cancer progression as well as the potential CD44-targeting therapy for cancer management. …

[HTML][HTML] Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
… c release, caspase 3 activity, and cleavage of poly (ADP-ribose) polymerase in vitro and
in vivo, suggesting p66(Shc) as a potential therapeutic target in endothelial dysfunction [48]. …

[HTML][HTML] HMGB1 as a potential biomarker and therapeutic target for severe COVID-19

R Chen, Y Huang, J Quan, J Liu, H Wang, TR Billiar… - Heliyon, 2020 - cell.com
… inflammation, could be a potential target for innovative therapeutic strategies for COVID-19. …
In this study, we provide evidence that HMGB1 could be a biomarker and therapeutic target

[HTML][HTML] Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

DR Wang, XL Wu, YL Sun - Signal transduction and targeted therapy, 2022 - nature.com
… Furthermore, as ICB and CAR-T cells have been the most rigorously evaluated immunotherapy
strategies in the clinic, we will also discuss biomarkers associated with the clinical …

Epigenetics of colorectal cancer: biomarker and therapeutic potential

G Jung, E Hernández-Illán, L Moreira… - Nature reviews …, 2020 - nature.com
… Unsurprisingly, in view of these key cancer-related activities, these enzymes are attracting
a lot of attention as potential therapeutic targets in various malignancies, including CRC 36 . …

[HTML][HTML] The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target

WT O'Brien, L Pham, GF Symons, M Monif… - Journal of …, 2020 - Springer
… the use of emerging biomarker platforms. Taken together, this review highlights the exciting
potential of the NLRP3 inflammasome as a target for treatments and biomarkers that may …

[HTML][HTML] Matrix metalloproteinases as potential biomarkers and therapeutic targets in liver diseases

E Geervliet, R Bansal - Cells, 2020 - mdpi.com
… their role as biomarkers. Finally, we highlight MMPs as promising therapeutic targets for the
… Here, we review the studies that have investigated MMPs as potential therapeutic targets for …

CXCL5/CXCR2 axis in tumor microenvironment as potential diagnostic biomarker and therapeutic target

W Zhang, H Wang, M Sun, X Deng, X Wu… - Cancer …, 2020 - Wiley Online Library
… as biomarkers for predicting prognosis and molecular targets … as potential prognostic
biomarkers and therapeutic targets in … the clinical application of many therapeutic targets [4]. In …

Multilevel omics for the discovery of biomarkers and therapeutic targets for stroke

J Montaner, L Ramiro, A Simats, S Tiedt… - Nature Reviews …, 2020 - nature.com
… , no biomarkers for stroke are … of therapeutic targets and biomarker discovery. In this Review,
we detail current knowledge on the pathology of stroke and the current status of biomarker