… Recently was been found that pyroptosis is a unique form of proinflammatory programmed
death, that is different from apoptosis. A growing number of studies have investigated …

… , potential molecular mechanism, and pathway-associated therapy in sepsis. Host-derived
molecules interacting with activated cells possess pivotal role for sepsis pathogenesis by …

… Overall, the interface between bloodstream and brain comprises an important factor
controlling sepsis-associated cerebral damage, and hence an ideal therapeutic target for treating …

… -CoV-2 infection and evaluating it as potential therapeutic target … -3/7 + apoptotic T cells in
a murine CLP model of sepsis, … an important mediator of sepsis-induced T cell apoptosis (34)…

… in sepsis. Our review provided an additional insight in the role of PCSK9 in sepsis, which
might serve as a potential target … In the presence of apoptosis of cerebral neurons, the PCSK9 …

… of sepsis, and confirms CHs’ potential as therapeutic targets in future sepsis management. …
Autophagy and apoptosis are also found in human umbilical vein endothelial cells (HUVECs…

… Our bioinformatics analysis clearly showed that the four identified core targets might beneficially
suppress sepsis-associated epithelial cell necrosis or apoptosis in the lung, peritoneum …

… Immunometabolic paralysis was suggested as a therapeutic target for the treatment of sepsis
48,59 . Indeed, defects in energy production by oxidative phosphorylation were very severe …

… potential in mouse sepsis models. In this review paper, we will focus discussion on how
intracellular LPS is a relevant, novel therapeutic target in sepsis… which targets both apoptotic and …

… Therefore, since MDSCs may be therapeutic target cells for sepsis-induced … CTLA-4
antibody treatment attenuates sepsis-induced apoptosis and improves survival in a …