Treatment outcomes and safety of mobocertinib in platinum-pretreated patients with EGFR exon 20 insertion–positive metastatic non–small cell lung cancer: a phase 1 …
C Zhou, SS Ramalingam, TM Kim, SW Kim… - JAMA …, 2021 - jamanetwork.com
… -pretreated patients (PPP) cohort and the EXCLAIM cohort. The PPP cohort included 114
patients with … The EXCLAIM cohort included 96 patients with previously treatedEGFRex20ins-…
patients with … The EXCLAIM cohort included 96 patients with previously treatedEGFRex20ins-…
… P224: Update from the Phase 2 registrational trial of repotrectinib in TKI-pretreated patients with ROS1+ advanced non-small cell lung cancer and with NTRK+ …
JJ Lin, BC Cho, C Springfeld, DR Camidge… - Molecular Cancer …, 2021 - AACR
… and 10% of patients with a TEAE that led to drug discontinuation. Updated efficacy information
for TKI-pretreated ROS1+ NSCLC and NTRK+ advanced solid tumor patients is being …
for TKI-pretreated ROS1+ NSCLC and NTRK+ advanced solid tumor patients is being …
Immunotherapeutic approaches for small-cell lung cancer
… In CheckMate 032, investigators evaluated tumour PD-L1 expression using the 28-8 pharmDx
antibody 47 in pretreatment tumour specimens obtained within 3 months of beginning ICI …
antibody 47 in pretreatment tumour specimens obtained within 3 months of beginning ICI …
Pretreatment neutrophil-to-lymphocyte ratio (NLR) may predict the outcomes of advanced non-small-cell lung cancer (NSCLC) patients treated with immune …
Y Li, Z Zhang, Y Hu, X Yan, Q Song, G Wang… - Frontiers in …, 2020 - frontiersin.org
… with advanced non-small-cell lung cancer (NSCLC) treated with immune checkpoint …
whether pretreatment NLR was associated with the outcomes of advanced NSCLC patients …
whether pretreatment NLR was associated with the outcomes of advanced NSCLC patients …
Clinical utility of pretreatment Glasgow prognostic score in non-small-cell lung cancer patients treated with immune checkpoint inhibitors
S Takamori, K Takada, M Shimokawa, T Matsubara… - Lung Cancer, 2021 - Elsevier
… In this retrospective study, we demonstrated that pretreatment GPS was the most robust
prognostic factor compared with mGPS and CAR in NSCLC patients treated with ICIs. This is the …
prognostic factor compared with mGPS and CAR in NSCLC patients treated with ICIs. This is the …
[HTML][HTML] … phase II trial of best supportive care with or without hyperthermia and vitamin C for heavily pretreated, advanced, refractory non-small-cell lung cancer
J Ou, X Zhu, P Chen, Y Du, Y Lu, X Peng, S Bao… - Journal of Advanced …, 2020 - Elsevier
… -small-cell lung cancer (NSCLC) patients. The aim of this trial was to further verify the efficacy
of the above combination therapy in previously treated patients with refractory advanced (…
of the above combination therapy in previously treated patients with refractory advanced (…
Long-Term Outcomes and Molecular Correlates of Sotorasib Efficacy in Patients With Pretreated KRAS G12C-Mutated Non–Small-Cell Lung Cancer: 2-Year Analysis …
… , and efficacy of sotorasib 960 mg once daily in patients with KRAS G12C-mutated, locally
advanced or metastatic non–small-cell lung cancer from the CodeBreaK 100 clinical trial (…
advanced or metastatic non–small-cell lung cancer from the CodeBreaK 100 clinical trial (…
Nivolumab in combination with stereotactic body radiotherapy in pretreated patients with metastatic renal cell carcinoma. Results of the phase II NIVES study
… The PEMBRO-RT study, a phase II randomized clinical trial that compares pembrolizumab
after SBRT with pembrolizumab alone in patients with advanced non–small cell lung cancer, …
after SBRT with pembrolizumab alone in patients with advanced non–small cell lung cancer, …
Atezolizumab versus docetaxel in pretreated patients with NSCLC: final results from the randomized phase 2 POPLAR and phase 3 OAK clinical trials
J Mazieres, A Rittmeyer, S Gadgeel, T Hida… - Journal of Thoracic …, 2021 - Elsevier
… Non–small cell lung cancer … to assess the benefit of these treatments in patients. The
pivotal studies of OAK and POPLAR in pretreated patients support evaluation of the long-term …
pivotal studies of OAK and POPLAR in pretreated patients support evaluation of the long-term …
Neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and outcomes with nivolumab in pretreated non-small cell lung cancer (NSCLC): a large …
A Russo, M Russano, T Franchina, MR Migliorino… - Advances in …, 2020 - Springer
… In conclusion, patients with pretreated NSCLC and high pretreatment levels of NLR (≥ 5)
and PLR (≥ 200) may experience inferior outcomes when treated with nivolumab. Therefore, …
and PLR (≥ 200) may experience inferior outcomes when treated with nivolumab. Therefore, …
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