Finding very high lipoprotein (a): the need for routine assessment

NS Nurmohamed, Y Kaiser… - … journal of preventive …, 2022 - academic.oup.com
evaluate the clinical impact of a single routine measurement of Lp(a) on cardiovascular
disease (CVD) risk reclassification and the potential implications for guideline-based preventive

Intensive low-density lipoprotein cholesterol lowering in cardiovascular disease prevention: opportunities and challenges

C Packard, MJ Chapman, M Sibartie, U Laufs… - Heart, 2021 - heart.bmj.com
Elevated levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased
risk of coronary heart disease and stroke. Guidelines for the management of dyslipidaemia …

Treatment and prevention of lipoprotein (a)-mediated cardiovascular disease: the emerging potential of RNA interference therapeutics

DI Swerdlow, DA Rider, A Yavari… - Cardiovascular …, 2022 - academic.oup.com
… In this review, we evaluate the causal role of Lp(a) across the cardiovascular disease spectrum,
examine the role of established lipid-modifying therapies in lowering Lp(a), and focus on …

Lipoprotein (a) and cardiovascular diseases

H Miksenas, JL Januzzi, P Natarajan - JAMA, 2021 - jamanetwork.com
… LDL cholesterol targets in the primary prevention setting. When evaluating LDL cholesterol
targets for patients treated for primary and secondary prevention, Lp(a) concentrations might …

[HTML][HTML] Lipid profile and lipoprotein (a) testing

KG Parhofer, U Laufs - Deutsches Ärzteblatt International, 2023 - ncbi.nlm.nih.gov
… The treatment of dyslipidemias plays a major role in the primary and secondary prevention
of cardiovascular disease. Proper evaluation of the patient’s lipid status is very important for …

Low-density lipoprotein cholesterol lowering treatment: the current approach

I Crismaru, A Pantea Stoian, OG Bratu… - Lipids in health and …, 2020 - Springer
… in terms of primary prevention, as well as in the secondary prevention of cardiovascular …
evaluated in studies currently in progress, with promising results so far. The future management

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM

MR Langlois, BG Nordestgaard, A Langsted… - Clinical Chemistry and …, 2020 - degruyter.com
… of ASCVD prevention is the harmonization of serum lipid and lipoprotein profiles produced …
on the quantification of atherogenic lipoproteins in nonfasting and fasting blood samples [1], [2…

Evaluating the association between low-density lipoprotein cholesterol reduction and relative and absolute effects of statin treatment: a systematic review and meta …

P Byrne, M Demasi, M Jones, SM Smith… - JAMA internal …, 2022 - jamanetwork.com
Importance The association between statin-induced reduction in low-density lipoprotein
cholesterol (LDL-C) levels and the absolute risk reduction of individual, rather than composite, …

Quantifying atherogenic lipoproteins for lipid-lowering strategies: consensus-based recommendations from EAS and EFLM

BG Nordestgaard, MR Langlois, A Langsted… - Atherosclerosis, 2020 - Elsevier
… of ASCVD prevention is the harmonisation of serum lipid and lipoprotein profiles produced …
on the quantification of atherogenic lipoproteins in nonfasting and fasting blood samples [1,2]. …

[HTML][HTML] Global think tank on the clinical considerations and management of lipoprotein (a): The top questions and answers regarding what clinicians need to know

SS Virani, ML Koschinsky, L Maher, A Mehta… - Progress in …, 2022 - Elsevier
Evidence from Mendelian randomization studies suggest that lipoprotein(a) (Lp(a)) has a
causal role in the development of atherosclerotic cardiovascular disease risk. However, …