[HTML][HTML] Involvement of neurokinin-1 receptors in the autonomic nervous system in colorectal distension-induced cardiovascular suppression in rats
K Kurogochi, M Uechi, K Orito - Frontiers in Pharmacology, 2022 - frontiersin.org
… neurokinin-1 receptor might be involved in the autonomic nervous system, and that a neurokinin-1
receptor … This study used a rat model in which the reflex was induced by afferent vagal …
receptor … This study used a rat model in which the reflex was induced by afferent vagal …
Neurokinins and their receptors in the rat trigeminal system: Differential localization and release with implications for migraine pain
… to come into focus was the neurokinin substance P (SP). This … its receptor can reduce monthly
migraine attacks drastically. … blocking neurokinin receptors showed no effect on migraine. …
migraine attacks drastically. … blocking neurokinin receptors showed no effect on migraine. …
[HTML][HTML] Neurokinin-1 receptor as a potential drug target for COVID-19 treatment
R Mehboob - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… In a study conducted on rats with respiratory infections caused by rat corona … cardiac
inflammation [59]. COVID-19 infected patients also undergo cardiac system malfunctioning or heart …
inflammation [59]. COVID-19 infected patients also undergo cardiac system malfunctioning or heart …
Cellular Metabolism of Substance P Produces Neurokinin-1 Receptor Peptide Agonists with diminished cyclic AMP Signaling
T Kriska, J Natarajan, A Herrnreiter… - … of Physiology-Cell …, 2024 - journals.physiology.org
… cardiovascular disease as well as diseases 551 affecting the central nervous and gastrointestinal
systems… properties and selectivities of three rat tachykinin receptors by transfection and …
systems… properties and selectivities of three rat tachykinin receptors by transfection and …
Neurokinin 2 receptor-mediated bladder and colorectal responses in aged spinal cord injured rats
… and defecation in adult SCI rats. This study compared the ability of a neurokinin 2 receptor
(NK2R) … to produce bladder and colorectal contractions in both young adult and aged SCI rats. …
(NK2R) … to produce bladder and colorectal contractions in both young adult and aged SCI rats. …
[HTML][HTML] Effects of a neurokinin-1 receptor antagonist in the acute phase after thoracic spinal cord injury in a rat model
G Zheng, AK Harms, M Tail, H Zhang… - Frontiers in Molecular …, 2023 - frontiersin.org
… However, the authors observed a significant increase of spinal cord edema compared to
uninjured rabbits 3 days after SCI which contrasts with our findings in rats 7 days after the injury. …
uninjured rabbits 3 days after SCI which contrasts with our findings in rats 7 days after the injury. …
Substance P/neurokinin1 receptor is associated with the expression of cardiac stem/pluripotency-associated genes in diabetic right and left atria
YM Jeong, S Lee, W Kim - 2021 - researchsquare.com
… that interacts with the G protein-coupled neurokinin-1 receptor (NK1R). Although the … in
heart damage 10. According to a recent study that constructed a rat model of right heart disease (…
heart damage 10. According to a recent study that constructed a rat model of right heart disease (…
The neuropeptide substance P/neurokinin‐1 receptor system and diabetes: From mechanism to therapy
F Kokabi, S Ebrahimi, F Mirzavi… - …, 2023 - Wiley Online Library
… , but had a stimulatory effect on glucagon secretion from normal rat pancreas. However, …
coronary artery disease in diabetic patients. It is known that the interaction of SP with its receptor …
coronary artery disease in diabetic patients. It is known that the interaction of SP with its receptor …
Neurokinin-1 receptor activation is sufficient to restore the hypercapnic ventilatory response in the Substance P-deficient naked mole-rat
MS Clayson, MEM Devereaux… - … , Integrative and …, 2020 - journals.physiology.org
… Naked mole-rats were group housed in interconnected multi-cage systems at 30C and 21%
O … Naked mole-rats that are housed within colony systems, as are our experimental animals, …
O … Naked mole-rats that are housed within colony systems, as are our experimental animals, …
Signaling and function of cardiac autonomic nervous system receptors: Insights from the GPCR signalling universe
A Lymperopoulos, N Cora, J Maning, AR Brill… - The FEBS …, 2021 - Wiley Online Library
… failure and hypertension to coronary artery disease, … In neonatal rat ventricular myocytes,
α 1 ARs recruit PDE4D to the β 2 … substance P, activating the neurokinin 1 receptor (NK 1 R); …
α 1 ARs recruit PDE4D to the β 2 … substance P, activating the neurokinin 1 receptor (NK 1 R); …
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